ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP's Holding History (CIK: 0001164508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 700,002 Value ($000) $18,431 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 313,753 Value ($000) $5,359 Avg Close $14.31 Range $11.51 - $17.60

Q3 2024

Shares 407,771 Value ($000) $5,118 Avg Close $10.89 Range $8.32 - $13.27

Q1 2024

Shares 581,558 Value ($000) $6 Avg Close $11.10 Range $9.64 - $13.14

Q4 2023

Shares 367,018 Value ($000) $4 Avg Close $7.97 Range $6.01 - $10.99

Q3 2023

Shares 472,005 Value ($000) $3 Avg Close $7.39 Range $6.11 - $8.80

Q2 2023

Shares 542,230 Value ($000) $5 Avg Close $8.95 Range $7.75 - $10.35

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	700,002	$18,431	$21.81	$16.00 - $28.49
Q3 2025	313,753	$5,359	$14.31	$11.51 - $17.60
Q3 2024	407,771	$5,118	$10.89	$8.32 - $13.27
Q1 2024	581,558	$6	$11.10	$9.64 - $13.14
Q4 2023	367,018	$4	$7.97	$6.01 - $10.99
Q3 2023	472,005	$3	$7.39	$6.11 - $8.80
Q2 2023	542,230	$5	$8.95	$7.75 - $10.35