ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022

Shares 1,708,472 Value ($000) $13,429 Avg Close $7.03 Range $4.86 - $9.28

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2022	1,708,472	$13,429	$7.03	$4.86 - $9.28