ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 381,621 Value ($000) $10,048 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 1,104,813 Value ($000) $18,870 Avg Close $14.31 Range $11.51 - $17.60

Q2 2025

Shares 116,102 Value ($000) $1,457 Avg Close $11.91 Range $9.03 - $13.44

Q1 2025

Shares 295,606 Value ($000) $3,521 Avg Close $13.64 Range $10.96 - $17.07

Q2 2023

Shares 55,718 Value ($000) $481 Avg Close $8.95 Range $7.75 - $10.35

Q1 2023

Shares 649,183 Value ($000) $6 Avg Close $8.72 Range $7.31 - $10.80

Q4 2022

Shares 115,522 Value ($000) $1 Avg Close $7.03 Range $4.86 - $9.28

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	381,621	$10,048	$21.81	$16.00 - $28.49
Q3 2025	1,104,813	$18,870	$14.31	$11.51 - $17.60
Q2 2025	116,102	$1,457	$11.91	$9.03 - $13.44
Q1 2025	295,606	$3,521	$13.64	$10.96 - $17.07
Q2 2023	55,718	$481	$8.95	$7.75 - $10.35
Q1 2023	649,183	$6	$8.72	$7.31 - $10.80
Q4 2022	115,522	$1	$7.03	$4.86 - $9.28