ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

Assenagon Asset Management S.A.'s Holding History (CIK: 0001546007)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 647,374 Value ($000) $17,045 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 1,326,774 Value ($000) $22,661 Avg Close $14.31 Range $11.51 - $17.60

Q2 2025

Shares 492,780 Value ($000) $6,184 Avg Close $11.91 Range $9.03 - $13.44

Q1 2025

Shares 495,067 Value ($000) $5,896 Avg Close $13.64 Range $10.96 - $17.07

Q4 2024

Shares 642,251 Value ($000) $9,403 Avg Close $13.98 Range $11.99 - $17.70

Q3 2024

Shares 331,144 Value ($000) $4,156 Avg Close $10.89 Range $8.32 - $13.27

Q1 2024

Shares 166,549 Value ($000) $1,752 Avg Close $11.10 Range $9.64 - $13.14

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	647,374	$17,045	$21.81	$16.00 - $28.49
Q3 2025	1,326,774	$22,661	$14.31	$11.51 - $17.60
Q2 2025	492,780	$6,184	$11.91	$9.03 - $13.44
Q1 2025	495,067	$5,896	$13.64	$10.96 - $17.07
Q4 2024	642,251	$9,403	$13.98	$11.99 - $17.70
Q3 2024	331,144	$4,156	$10.89	$8.32 - $13.27
Q1 2024	166,549	$1,752	$11.10	$9.64 - $13.14