ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

ACUTA CAPITAL PARTNERS, LLC's Holding History (CIK: 0001582844)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 80,143 Value ($000) $2,110 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 80,143 Value ($000) $1,369 Avg Close $14.31 Range $11.51 - $17.60

Q2 2025

Shares 83,655 Value ($000) $1,050 Avg Close $11.91 Range $9.03 - $13.44

Q1 2025

Shares 68,459 Value ($000) $815 Avg Close $13.64 Range $10.96 - $17.07

Q4 2024

Shares 67,240 Value ($000) $984 Avg Close $13.98 Range $11.99 - $17.70

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	80,143	$2,110	$21.81	$16.00 - $28.49
Q3 2025	80,143	$1,369	$14.31	$11.51 - $17.60
Q2 2025	83,655	$1,050	$11.91	$9.03 - $13.44
Q1 2025	68,459	$815	$13.64	$10.96 - $17.07
Q4 2024	67,240	$984	$13.98	$11.99 - $17.70