ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

Nuveen, LLC's Holding History (CIK: 0001871926)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 648,326 Value ($000) $17,070 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 565,385 Value ($000) $9,657 Avg Close $14.31 Range $11.51 - $17.60

Q2 2025

Shares 654,916 Value ($000) $8,219 Avg Close $11.91 Range $9.03 - $13.44

Q1 2025

Shares 198,812 Value ($000) $2,368 Avg Close $13.64 Range $10.96 - $17.07

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	648,326	$17,070	$21.81	$16.00 - $28.49
Q3 2025	565,385	$9,657	$14.31	$11.51 - $17.60
Q2 2025	654,916	$8,219	$11.91	$9.03 - $13.44
Q1 2025	198,812	$2,368	$13.64	$10.96 - $17.07