ZYMEWORKS INC

Ticker: ZYME CUSIP: 98985Y108 Class: Common Stock

Federation des caisses Desjardins du Quebec's Holding History (CIK: 0002022297)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 570 Value ($000) $15 Avg Close $21.81 Range $16.00 - $28.49

Q3 2025

Shares 870 Value ($000) $15 Avg Close $14.31 Range $11.51 - $17.60

Q2 2025

Shares 870 Value ($000) $11 Avg Close $11.91 Range $9.03 - $13.44

Q1 2025

Shares 870 Value ($000) $10 Avg Close $13.64 Range $10.96 - $17.07

Q4 2024

Shares 60 Value ($000) $1 Avg Close $13.98 Range $11.99 - $17.70

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	570	$15	$21.81	$16.00 - $28.49
Q3 2025	870	$15	$14.31	$11.51 - $17.60
Q2 2025	870	$11	$11.91	$9.03 - $13.44
Q1 2025	870	$10	$13.64	$10.96 - $17.07
Q4 2024	60	$1	$13.98	$11.99 - $17.70