ZYNERBA PHARMACEUTICALS INC

CUSIP: 98986X109 Class: COM

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2020
Shares 100,000 Value ($000) $383 Avg Close — Range —
Q1 2017
Shares 100,000 Value ($000) $2,010 Avg Close — Range —