CRESCENT BIOPHARMA INC.

Ticker: CBIO CUSIP: G2545C104 Class: COM

Jefferies Financial Group Inc.'s Holding History (CIK: 0000096223)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 64,244 Value ($000) $762 Avg Close $12.74 Range $9.81 - $16.35

Q3 2025

Shares 102,714 Value ($000) $1,221 Avg Close $13.27 Range $10.83 - $17.39

Q2 2025

Shares 27,096 Value ($000) $437 Avg Close $21.15 Range $11.06 - $29.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	64,244	$762	$12.74	$9.81 - $16.35
Q3 2025	102,714	$1,221	$13.27	$10.83 - $17.39
Q2 2025	27,096	$437	$21.15	$11.06 - $29.00