CRESCENT BIOPHARMA INC.

Ticker: CBIO CUSIP: G2545C104 Class: COM

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,133,514 Value ($000) $49,023 Avg Close $12.74 Range $9.81 - $16.35

Q3 2025

Shares 1,414,680 Value ($000) $16,821 Avg Close $13.27 Range $10.83 - $17.39

Q2 2025

Shares 1,414,190 Value ($000) $22,825 Avg Close $21.15 Range $11.06 - $29.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,133,514	$49,023	$12.74	$9.81 - $16.35
Q3 2025	1,414,680	$16,821	$13.27	$10.83 - $17.39
Q2 2025	1,414,190	$22,825	$21.15	$11.06 - $29.00