CRESCENT BIOPHARMA INC.

Ticker: CBIO CUSIP: G2545C104 Class: COM

DRIEHAUS CAPITAL MANAGEMENT LLC's Holding History (CIK: 0000938206)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 302,457 Value ($000) $3,587 Avg Close $12.74 Range $9.81 - $16.35

Q3 2025

Shares 302,457 Value ($000) $3,596 Avg Close $13.27 Range $10.83 - $17.39

Q2 2025

Shares 302,457 Value ($000) $4,882 Avg Close $21.15 Range $11.06 - $29.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	302,457	$3,587	$12.74	$9.81 - $16.35
Q3 2025	302,457	$3,596	$13.27	$10.83 - $17.39
Q2 2025	302,457	$4,882	$21.15	$11.06 - $29.00