CRESCENT BIOPHARMA INC.

Ticker: CBIO CUSIP: G2545C104 Class: COM

TANG CAPITAL MANAGEMENT LLC's Holding History (CIK: 0001232621)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 872,398 Value ($000) $10,347 Avg Close $12.74 Range $9.81 - $16.35

Q3 2025

Shares 679,824 Value ($000) $8,083 Avg Close $13.27 Range $10.83 - $17.39

Q2 2025

Shares 50,152 Value ($000) $809 Avg Close $21.15 Range $11.06 - $29.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	872,398	$10,347	$12.74	$9.81 - $16.35
Q3 2025	679,824	$8,083	$13.27	$10.83 - $17.39
Q2 2025	50,152	$809	$21.15	$11.06 - $29.00