HORIZON PHARMA PLC

CUSIP: G4617B105 Class: SHS

Redmile Group, LLC's Holding History (CIK: 0001425738)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018
Shares 25,800 Value ($000) $427 Avg Close — Range —
Q1 2018
Shares 20,000 Value ($000) $284 Avg Close — Range —
Q4 2017
Shares 20,000 Value ($000) $292 Avg Close — Range —