MEDTRONIC PLC

Ticker: MDT CUSIP: G5960L103 Class: SHS

ORBIMED ADVISORS LLC's Holding History (CIK: 0001055951)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017

Shares 254,200 Value ($000) $20,527 Avg Close $64.98 Range $62.07 - $68.23

Q3 2017

Shares 879,000 Value ($000) $68,360 Avg Close $66.95 Range $62.45 - $71.85

Q2 2017

Shares 879,000 Value ($000) $78,011 Avg Close $67.64 Range $63.89 - $71.97

Q1 2017

Shares 766,600 Value ($000) $61,757 Avg Close $62.37 Range $55.34 - $67.03

Q4 2016

Shares 766,600 Value ($000) $54,605 Avg Close $62.35 Range $56.35 - $68.81

Q3 2016

Shares 766,600 Value ($000) $66,234 Avg Close $68.78 Range $66.52 - $70.46

Q2 2016

Shares 666,299 Value ($000) $57,815 Avg Close $63.51 Range $58.39 - $68.26

Q1 2016

Shares 666,299 Value ($000) $49,972 Avg Close $58.89 Range $55.50 - $61.14

Q4 2015

Shares 588,299 Value ($000) $45,252 Avg Close $58.56 Range $51.59 - $61.36

Q3 2015

Shares 588,299 Value ($000) $39,381 Avg Close $56.98 Range $42.95 - $61.02

Q2 2015

Shares 646,300 Value ($000) $47,891 Avg Close $58.80 Range $56.64 - $60.84

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2017	254,200	$20,527	$64.98	$62.07 - $68.23
Q3 2017	879,000	$68,360	$66.95	$62.45 - $71.85
Q2 2017	879,000	$78,011	$67.64	$63.89 - $71.97
Q1 2017	766,600	$61,757	$62.37	$55.34 - $67.03
Q4 2016	766,600	$54,605	$62.35	$56.35 - $68.81
Q3 2016	766,600	$66,234	$68.78	$66.52 - $70.46
Q2 2016	666,299	$57,815	$63.51	$58.39 - $68.26
Q1 2016	666,299	$49,972	$58.89	$55.50 - $61.14
Q4 2015	588,299	$45,252	$58.56	$51.59 - $61.36
Q3 2015	588,299	$39,381	$56.98	$42.95 - $61.02
Q2 2015	646,300	$47,891	$58.80	$56.64 - $60.84