Location: New York, NY
CIK: 0001055951 · Show all filings
Period: Q1 2026 (← Previous) (Next →)
Filing Date: May 15, 2026
Total Value: $5.045B (97.5% shares, 2.5% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| EWTX | EDGEWISE THERAPEUTICS INC | 15,518,492 | $489M | 9.7% | — | — | COM | 28036F105 |
| ELVN | ENLIVEN THERAPEUTICS INC | 7,959,538 | $312M | 6.2% | — | — | COM | 29337E102 |
| MDXH | MDXHEALTH SA | 124,306,000 | $286M | 5.7% | — | — | Call | B5950S113 |
| LLY | ELI LILLY & CO | 236,800 | $218M | 4.3% | — | — | COM | 532457108 |
| SVA | SINOVAC BIOTECH LTD | 2,718,735 | $184M | 3.7% | — | — | SHS | P8696W104 |
| RCEL | AVITA MEDICAL INC | 40,966,100 | $154M | 3.1% | — | — | Call | 05380C102 |
| BSX | BOSTON SCIENTIFIC CORP | 2,382,100 | $149M | 3.0% | — | — | COM | 101137107 |
| SION | SIONNA THERAPEUTICS INC | 3,530,702 | $142M | 2.8% | — | — | COM | 829401108 |
| AZN | ASTRAZENECA PLC | 670,200 | $132M | 2.6% | — | — | ORD | G0593M107 |
| MYGN | MYRIAD GENETICS INC | 125,000,000 | $123M | 2.4% | — | — | COM | 62855J104 |
| MBX | MBX BIOSCIENCES INC | 3,637,887 | $109M | 2.2% | — | — | COM | 55287L101 |
| CRVS | CORVUS PHARMACEUTICALS INC | 7,165,006 | $105M | 2.1% | — | — | COM | 221015100 |
| ARGX | ARGENX SE | 136,900 | $99.97M | 2.0% | — | — | SPONSORED ADR | 04016X101 |
| EW | EDWARDS LIFESCIENCES CORP | 1,230,600 | $98.55M | 2.0% | — | — | COM | 28176E108 |
| ISRG | INTUITIVE SURGICAL INC | 208,700 | $96.21M | 1.9% | — | — | COM NEW | 46120E602 |
| CMPX | COMPASS THERAPEUTICS INC | 15,219,994 | $80.51M | 1.6% | — | — | COM | 20454B104 |
| MRK | MERCK & CO INC | 663,400 | $79.8M | 1.6% | — | — | COM | 58933Y105 |
| GPCR | STRUCTURE THERAPEUTICS INC | 1,475,403 | $71.11M | 1.4% | — | — | SPONSORED ADS | 86366E106 |
| AVBP | ARRIVENT BIOPHARMA INC | 3,027,328 | $69.84M | 1.4% | — | — | COM | 04272N102 |
| IRON | DISC MEDICINE INC | 1,067,550 | $68.26M | 1.4% | — | — | COM | 254604101 |
| SPRY | ARS PHARMACEUTICALS INC | 8,288,510 | $66.56M | 1.3% | — | — | COM | 82835W108 |
| CGON | CG ONCOLOGY INC | 948,267 | $64.18M | 1.3% | — | — | COM | 156944100 |
| XENE | XENON PHARMACEUTICALS INC | 1,059,971 | $61.64M | 1.2% | — | — | COM | 98420N105 |
| SYK | STRYKER CORPORATION | 182,500 | $59.97M | 1.2% | — | — | COM | 863667101 |
| BMY | BRISTOL-MYERS SQUIBB CO | 925,000 | $56.1M | 1.1% | — | — | COM | 110122108 |
| MLYS | MINERALYS THERAPEUTICS INC | 2,052,900 | $55.61M | 1.1% | — | — | COM | 603170101 |
| PRAX | PRAXIS PRECISION MEDICINES I | 172,500 | $55.58M | 1.1% | — | — | COM NEW | 74006W207 |
| PFE | PFIZER INC | 1,946,500 | $54.66M | 1.1% | — | — | COM | 717081103 |
| DYN | DYNE THERAPEUTICS INC | 2,917,884 | $52.9M | 1.0% | — | — | COM | 26818M108 |
| NTRA | NATERA INC | 262,000 | $52.4M | 1.0% | — | — | COM | 632307104 |
| ABVX | ABIVAX SA | 465,700 | $51.86M | 1.0% | — | — | SPONSORED ADS | 00370M103 |
| UPB | UPSTREAM BIO INC | 5,693,589 | $51.24M | 1.0% | — | — | COM | 91678A107 |
| DHR | DANAHER CORP DEL | 265,800 | $50.4M | 1.0% | — | — | COM | 235851102 |
| CAI | CARIS LIFE SCIENCES INC | 2,806,811 | $50.19M | 1.0% | — | — | COM | 142152107 |
| RCEL | AVITA MEDICAL INC | 41,044,895 | $42.52M | 0.8% | — | — | COM | 05380C102 |
| ASND | ASCENDIS PHARMA A/S | 181,977 | $41.62M | 0.8% | — | — | SPONSORED ADR | 04351P101 |
| STTK | SHATTUCK LABS INC | 6,306,127 | $40.55M | 0.8% | — | — | COM | 82024L103 |
| GH | GUARDANT HEALTH INC | 435,200 | $40.2M | 0.8% | — | — | COM | 40131M109 |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 119,000 | $39.37M | 0.8% | — | — | COM | 02043Q107 |
| PRLD | PRELUDE THERAPEUTICS INC | 10,909,256 | $37.31M | 0.7% | — | — | COM | 74065P101 |
| CRNX | CRINETICS PHARMACEUTICALS IN | 999,000 | $36.28M | 0.7% | — | — | COM | 22663K107 |
| AXSM | AXSOME THERAPEUTICS INC. | 213,921 | $36.16M | 0.7% | — | — | COM | 05464T104 |
| QURE | UNIQURE NV | 2,136,149 | $34.93M | 0.7% | — | — | SHS | N90064101 |
| ORIC | ORIC PHARMACEUTICALS INC | 2,693,929 | $34.13M | 0.7% | — | — | COM | 68622P109 |
| ELV | ELEVANCE HEALTH INC FORMERLY | 114,700 | $33.58M | 0.7% | — | — | COM | 036752103 |
| RLMD | RELMADA THERAPEUTICS INC | 4,715,864 | $32.82M | 0.7% | — | — | COM | 75955J402 |
| FBRX | FORTE BIOSCIENCES INC | 1,196,955 | $31M | 0.6% | — | — | COM NEW | 34962G208 |
| TRVI | TREVI THERAPEUTICS INC | 2,454,400 | $29.28M | 0.6% | — | — | COM | 89532M101 |
| ESPR | ESPERION THERAPEUTICS INC NE | 10,570,300 | $28.96M | 0.6% | — | — | COM | 29664W105 |
| NPCE | NEUROPACE INC | 2,096,527 | $27.57M | 0.5% | — | — | COM | 641288105 |
| RYTM | RHYTHM PHARMACEUTICALS INC | 314,100 | $27.32M | 0.5% | — | — | COM | 76243J105 |
| TMO | THERMO FISHER SCIENTIFIC INC | 46,500 | $22.86M | 0.5% | — | — | COM | 883556102 |
| SNDX | SYNDAX PHARMACEUTICALS INC | 962,300 | $22.48M | 0.4% | — | — | COM | 87164F105 |
| — | IMAGENEBIO INC | 6,210,899 | $22.08M | 0.4% | — | — | NONVOTING | 000000000 |
| BTSG | BRIGHTSPRING HEALTH SVCS INC | 497,800 | $21.21M | 0.4% | — | — | COM | 10950A106 |
| LXEO | LEXEO THERAPEUTICS INC | 3,602,450 | $20.68M | 0.4% | — | — | COM | 52886X107 |
| STRO | SUTRO BIOPHARMA INC | 801,144 | $19.96M | 0.4% | — | — | COM SHS | 869367201 |
| NKTR | NEKTAR THERAPEUTICS | 275,000 | $19.79M | 0.4% | — | — | COM NEW | 640268306 |
| HELP | CYBIN INC | 3,832,843 | $18.4M | 0.4% | — | — | COM NEW | 23256X407 |
| KRYS | KRYSTAL BIOTECH INC | 69,100 | $17.85M | 0.4% | — | — | COM | 501147102 |
| PVLA | PALVELLA THERAPEUTICS INC NE | 134,600 | $16.78M | 0.3% | — | — | COM | 697947109 |
| CRBP | CORBUS PHARMACEUTICALS HLDGS | 1,737,287 | $16.31M | 0.3% | — | — | COM NEW | 21833P301 |
| URGN | UROGEN PHARMA LTD | 875,487 | $15.74M | 0.3% | — | — | COM | M96088105 |
| DFTX | DEFINIUM THERAPEUTICS INC | 804,000 | $15.2M | 0.3% | — | — | COM SHS | 24477V105 |
| VERA | VERA THERAPEUTICS INC | 369,596 | $14.87M | 0.3% | — | — | CL A | 92337R101 |
| QTTB | Q32 BIO INC | 2,252,987 | $14.46M | 0.3% | — | — | COM | 746964105 |
| WHWK | WHITEHAWK THERAPEUTICS INC | 4,166,000 | $14.37M | 0.3% | — | — | COM | 00032Q104 |
| AMGN | AMGEN INC | 39,900 | $14.04M | 0.3% | — | — | COM | 031162100 |
| ALHC | ALIGNMENT HEALTHCARE INC | 791,000 | $13.94M | 0.3% | — | — | COM | 01625V104 |
| EYPT | EYEPOINT INC | 1,069,147 | $13.78M | 0.3% | — | — | COM NEW | 30233G209 |
| JANX | JANUX THERAPEUTICS INC | 983,600 | $13.67M | 0.3% | — | — | COM | 47103J105 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | 1,425,200 | $13.57M | 0.3% | — | — | COM | 09058V103 |
| BCAX | BICARA THERAPEUTICS INC | 667,300 | $13.27M | 0.3% | — | — | COM | 055477103 |
| BIOA | BIOAGE LABS INC | 711,811 | $12.45M | 0.2% | — | — | COM | 09077V100 |
| COGT | COGENT BIOSCIENCES INC | 322,100 | $12.4M | 0.2% | — | — | COM | 19240Q201 |
| ALMS | ALUMIS INC | 548,163 | $12.08M | 0.2% | — | — | COM | 022307102 |
| REGN | REGENERON PHARMACEUTICALS | 14,700 | $11.36M | 0.2% | — | — | COM | 75886F107 |
| CARL | CARLSMED INC | 1,252,600 | $11.34M | 0.2% | — | — | COM | 14280C105 |
| BIIB | BIOGEN INC | 61,600 | $11.29M | 0.2% | — | — | COM | 09062X103 |
| QGEN | QIAGEN NV | 250,000 | $10.01M | 0.2% | — | — | Call | N72482156 |
| KNSA | KINIKSA PHARMACEUTICALS INTL | 180,599 | $8.696M | 0.2% | — | — | ORD SHS CL A | G52694109 |
| KROS | KEROS THERAPEUTICS INC | 759,155 | $8.381M | 0.2% | — | — | COM | 492327101 |
| GILD | GILEAD SCIENCES INC | 59,600 | $8.306M | 0.2% | — | — | COM | 375558103 |
| HRTX | HERON THERAPEUTICS INC | 9,816,940 | $7.855M | 0.2% | — | — | COM | 427746102 |
| AVTX | AVALO THERAPEUTICS INC | 475,165 | $7.094M | 0.1% | — | — | COM NEW | 05338F306 |
| TECX | TECTONIC THERAPEUTIC INC | 226,600 | $7.004M | 0.1% | — | — | COM | 878972108 |
| ACET | ADICET BIO INC | 1,027,944 | $7M | 0.1% | — | — | COM NEW | 007002207 |
| CMPS | COMPASS PATHWAYS PLC | 1,150,646 | $6.363M | 0.1% | — | — | SPONSORED ADS | 20451W101 |
| PVLA | PALVELLA THERAPEUTICS INC NE | 50,000 | $6.232M | 0.1% | — | — | Call | 697947109 |
| PHVS | PHARVARIS N V | 205,400 | $5.803M | 0.1% | — | — | COM | N69605108 |
| ALXO | ALX ONCOLOGY HLDGS INC | 2,866,256 | $5.747M | 0.1% | — | — | COM | 00166B105 |
| AORT | ARTIVION INC | 151,000 | $5.53M | 0.1% | — | — | COM | 228903100 |
| NSPR | INSPIREMD INC | 3,133,405 | $5.107M | 0.1% | — | — | COM | 45779A846 |
| RVMD | REVOLUTION MEDICINES INC | 52,000 | $5.057M | 0.1% | — | — | COM | 76155X100 |
| ADCT | ADC THERAPEUTICS SA | 1,318,026 | $4.943M | 0.1% | — | — | SHS | H0036K147 |
| PTGX | PROTAGONIST THERAPEUTICS INC | 42,100 | $4.437M | 0.1% | — | — | COM | 74366E102 |
| PALI | PALISADE BIO INC | 2,333,000 | $4.083M | 0.1% | — | — | COM | 696389402 |
| ANRO | ALTO NEUROSCIENCE INC | 167,500 | $3.765M | 0.1% | — | — | COM SHS | 02157Q109 |
| SVRA | SAVARA INC | 635,000 | $3.467M | 0.1% | — | — | COM | 805111101 |
| CGEM | CULLINAN THERAPEUTICS INC | 243,006 | $3.453M | 0.1% | — | — | COM | 230031106 |
| SLNO | SOLENO THERAPEUTICS INC | 100,000 | $3.348M | 0.1% | — | — | Call | 834203309 |
| PTCT | PTC THERAPEUTICS INC | 49,100 | $3.345M | 0.1% | — | — | COM | 69366J200 |
| LFST | LIFESTANCE HEALTH GROUP INC | 500,000 | $3.185M | 0.1% | — | — | COM | 53228F101 |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | 40,000 | $2.919M | 0.1% | — | — | COM NEW | 10919W405 |
| JBIO | JADE BIOSCIENCES INC | 185,011 | $2.599M | 0.1% | — | — | COM NEW | 008064206 |
| CCCC | C4 THERAPEUTICS INC | 856,353 | $2.252M | 0.0% | — | — | COM STK | 12529R107 |
| KALV | KALVISTA PHARMACEUTICALS INC | 94,400 | $1.9M | 0.0% | — | — | COM | 483497103 |
| IMA | IMAGENEBIO INC | 378,556 | $1.893M | 0.0% | — | — | COM | 45175G207 |
| VTGN | VISTAGEN THERAPEUTICS INC | 3,060,000 | $1.749M | 0.0% | — | — | COM | 92840H400 |
| ATAI | ATAIBECKLEY INC | 347,000 | $1.228M | 0.0% | — | — | COM SHS | 04650F101 |
| — | COGENT BIOSCIENCES INC | 1,000,000 | $1.22M | 0.0% | — | — | NOTE 1.625%11/1 | 19240QAA0 |
| TRAW | TRAWS PHARMA INC | 605,531 | $1.108M | 0.0% | — | — | COM NEW | 68232V884 |