PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

GREAT POINT PARTNERS LLC's Holding History (CIK: 0001281446)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020

Shares 977,647 Value ($000) $11,742 Avg Close $11.83 Range $9.86 - $14.14

Q3 2020

Shares 1,548,479 Value ($000) $15,469 Avg Close $12.03 Range $9.67 - $13.78

Q2 2020

Shares 2,082,841 Value ($000) $21,787 Avg Close $11.11 Range $9.25 - $12.98

Q1 2020

Shares 2,082,841 Value ($000) $22,286 Avg Close $12.11 Range $7.10 - $16.05

Q4 2019

Shares 2,100,941 Value ($000) $33,258 Avg Close $10.72 Range $7.40 - $17.63

Q3 2019

Shares 2,066,041 Value ($000) $16,198 Avg Close $8.88 Range $6.71 - $10.70

Q2 2019

Shares 1,676,250 Value ($000) $17,718,000 Avg Close $10.27 Range $8.67 - $12.54

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2020	977,647	$11,742	$11.83	$9.86 - $14.14
Q3 2020	1,548,479	$15,469	$12.03	$9.67 - $13.78
Q2 2020	2,082,841	$21,787	$11.11	$9.25 - $12.98
Q1 2020	2,082,841	$22,286	$12.11	$7.10 - $16.05
Q4 2019	2,100,941	$33,258	$10.72	$7.40 - $17.63
Q3 2019	2,066,041	$16,198	$8.88	$6.71 - $10.70
Q2 2019	1,676,250	$17,718,000	$10.27	$8.67 - $12.54