PROTHENA CORP PLC

Ticker: PRTA CUSIP: G72800108 Class: Common Stock

Frazier Life Sciences Management, L.P.'s Holding History (CIK: 0001892134)

Note: Option positions (PUT/CALL) are excluded.

Q3 2023

Shares 127,900 Value ($000) $6,171 Avg Close $59.41 Range $45.22 - $73.14

Q2 2023

Shares 127,900 Value ($000) $8,733 Avg Close $64.50 Range $47.45 - $79.65

Q1 2023

Shares 127,900 Value ($000) $6,199 Avg Close $52.83 Range $45.06 - $60.82

Q4 2022

Shares 127,900 Value ($000) $7,706 Avg Close $58.56 Range $50.89 - $66.47

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2023	127,900	$6,171	$59.41	$45.22 - $73.14
Q2 2023	127,900	$8,733	$64.50	$47.45 - $79.65
Q1 2023	127,900	$6,199	$52.83	$45.06 - $60.82
Q4 2022	127,900	$7,706	$58.56	$50.89 - $66.47