STRONGBRIDGE BIOPHARMA PLC

CUSIP: G85347105 Class: SHS USD

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q3 2019
Shares 490,000 Value ($000) $1,171 Avg Close — Range —
Q2 2019
Shares 1,140,000 Value ($000) $3,568 Avg Close — Range —
Q1 2019
Shares 1,152,500 Value ($000) $5,739 Avg Close — Range —
Q4 2018
Shares 1,390,000 Value ($000) $6,227 Avg Close — Range —
Q3 2018
Shares 1,730,000 Value ($000) $8,390 Avg Close — Range —
Q2 2018
Shares 1,830,000 Value ($000) $10,980 Avg Close — Range —
Q1 2018
Shares 1,590,000 Value ($000) $14,071 Avg Close — Range —
Q4 2017
Shares 1,250,000 Value ($000) $9,062 Avg Close — Range —
Q3 2017
Shares 1,180,000 Value ($000) $8,142 Avg Close — Range —
Q2 2017
Shares 1,180,000 Value ($000) $8,437 Avg Close — Range —
Q1 2017
Shares 1,180,000 Value ($000) $5,605 Avg Close — Range —
Q4 2016
Shares 1,160,000 Value ($000) $2,784 Avg Close — Range —