CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP's Holding History (CIK: 0001164508)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022

Shares 29,162 Value ($000) $1,772 Avg Close $58.79 Range $42.51 - $75.42

Q3 2021

Shares 47,100 Value ($000) $5,272 Avg Close $125.59 Range $109.63 - $163.00

Q2 2021

Shares 81,000 Value ($000) $13,113 Avg Close $121.62 Range $95.11 - $169.76

Q3 2020

Shares 6,281 Value ($000) $525 Avg Close $88.70 Range $74.00 - $105.12

Q1 2020

Shares 260,996 Value ($000) $11,069 Avg Close $51.63 Range $32.30 - $64.19

Q4 2019

Shares 103,800 Value ($000) $6,322 Avg Close $54.60 Range $35.46 - $74.00

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2022	29,162	$1,772	$58.79	$42.51 - $75.42
Q3 2021	47,100	$5,272	$125.59	$109.63 - $163.00
Q2 2021	81,000	$13,113	$121.62	$95.11 - $169.76
Q3 2020	6,281	$525	$88.70	$74.00 - $105.12
Q1 2020	260,996	$11,069	$51.63	$32.30 - $64.19
Q4 2019	103,800	$6,322	$54.60	$35.46 - $74.00