CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 30,492 Value ($000) $1,599 Avg Close $59.89 Range $48.02 - $78.48

Q3 2025

Shares 86,282 Value ($000) $5,592 Avg Close $57.41 Range $46.60 - $71.13

Q2 2025

Shares 70,093 Value ($000) $3,409 Avg Close $38.70 Range $30.04 - $51.52

Q1 2025

Shares 583,733 Value ($000) $19,864 Avg Close $42.39 Range $32.96 - $55.88

Q4 2024

Shares 8,498 Value ($000) $334 Avg Close $47.22 Range $38.20 - $59.07

Q3 2024

Shares 110,085 Value ($000) $5,172 Avg Close $50.74 Range $43.42 - $63.68

Q2 2024

Shares 26,326 Value ($000) $1,422 Avg Close $57.84 Range $51.02 - $68.39

Q1 2024

Shares 105,643 Value ($000) $7,201 Avg Close $71.59 Range $58.29 - $91.10

Q4 2023

Shares 17,270 Value ($000) $1,081 Avg Close $55.02 Range $37.55 - $76.97

Q3 2023

Shares 136,230 Value ($000) $6,183 Avg Close $51.65 Range $44.53 - $59.67

Q2 2023

Shares 62,247 Value ($000) $3,495 Avg Close $56.74 Range $43.10 - $72.00

Q1 2023

Shares 229,977 Value ($000) $10 Avg Close $48.57 Range $39.88 - $58.50

Q4 2022

Shares 12,144 Value ($000) $0 Avg Close $53.05 Range $38.94 - $66.31

Q3 2022

Shares 9,611 Value ($000) $628 Avg Close $72.47 Range $60.41 - $86.95

Q1 2022

Shares 45,788 Value ($000) $2,874 Avg Close $62.79 Range $50.54 - $79.40

Q4 2021

Shares 385,866 Value ($000) $29,241 Avg Close $87.36 Range $67.15 - $112.39

Q3 2021

Shares 191,700 Value ($000) $21,457 Avg Close $125.59 Range $109.63 - $163.00

Q2 2021

Shares 92,639 Value ($000) $14,997 Avg Close $121.62 Range $95.11 - $169.76

Q1 2021

Shares 103,112 Value ($000) $12,564 Avg Close $151.00 Range $100.00 - $220.20

Q4 2020

Shares 22,185 Value ($000) $3,397 Avg Close $118.20 Range $79.31 - $181.42

Q2 2020

Shares 20,592 Value ($000) $1,513 Avg Close $58.47 Range $38.10 - $79.92

Q4 2019

Shares 312,433 Value ($000) $19,029 Avg Close $54.60 Range $35.46 - $74.00

Q3 2019

Shares 106,538 Value ($000) $4,366 Avg Close $47.78 Range $40.70 - $53.90

Q3 2018

Shares 67,179 Value ($000) $2,979 Avg Close $52.37 Range $43.68 - $66.26

Q4 2017

Shares 95,130 Value ($000) $2,234 Avg Close $19.00 Range $16.51 - $25.00

Q3 2017

Shares 75,272 Value ($000) $1,345 Avg Close $18.13 Range $15.55 - $21.32

Q2 2017

Shares 33,000 Value ($000) $529 Avg Close $16.52 Range $13.50 - $22.22

Q4 2016

Shares 11,913 Value ($000) $241 Avg Close $18.69 Range $13.75 - $23.97

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	30,492	$1,599	$59.89	$48.02 - $78.48
Q3 2025	86,282	$5,592	$57.41	$46.60 - $71.13
Q2 2025	70,093	$3,409	$38.70	$30.04 - $51.52
Q1 2025	583,733	$19,864	$42.39	$32.96 - $55.88
Q4 2024	8,498	$334	$47.22	$38.20 - $59.07
Q3 2024	110,085	$5,172	$50.74	$43.42 - $63.68
Q2 2024	26,326	$1,422	$57.84	$51.02 - $68.39
Q1 2024	105,643	$7,201	$71.59	$58.29 - $91.10
Q4 2023	17,270	$1,081	$55.02	$37.55 - $76.97
Q3 2023	136,230	$6,183	$51.65	$44.53 - $59.67
Q2 2023	62,247	$3,495	$56.74	$43.10 - $72.00
Q1 2023	229,977	$10	$48.57	$39.88 - $58.50
Q4 2022	12,144	$0	$53.05	$38.94 - $66.31
Q3 2022	9,611	$628	$72.47	$60.41 - $86.95
Q1 2022	45,788	$2,874	$62.79	$50.54 - $79.40
Q4 2021	385,866	$29,241	$87.36	$67.15 - $112.39
Q3 2021	191,700	$21,457	$125.59	$109.63 - $163.00
Q2 2021	92,639	$14,997	$121.62	$95.11 - $169.76
Q1 2021	103,112	$12,564	$151.00	$100.00 - $220.20
Q4 2020	22,185	$3,397	$118.20	$79.31 - $181.42
Q2 2020	20,592	$1,513	$58.47	$38.10 - $79.92
Q4 2019	312,433	$19,029	$54.60	$35.46 - $74.00
Q3 2019	106,538	$4,366	$47.78	$40.70 - $53.90
Q3 2018	67,179	$2,979	$52.37	$43.68 - $66.26
Q4 2017	95,130	$2,234	$19.00	$16.51 - $25.00
Q3 2017	75,272	$1,345	$18.13	$15.55 - $21.32
Q2 2017	33,000	$529	$16.52	$13.50 - $22.22
Q4 2016	11,913	$241	$18.69	$13.75 - $23.97