CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

CANADA PENSION PLAN INVESTMENT BOARD's Holding History (CIK: 0001283718)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022

Shares 2,200 Value ($000) $89 Avg Close $53.05 Range $38.94 - $66.31

Q2 2022

Shares 5,500 Value ($000) $334 Avg Close $58.79 Range $42.51 - $75.42

Q3 2021

Shares 80,978 Value ($000) $9,064 Avg Close $125.59 Range $109.63 - $163.00

Q2 2021

Shares 80,978 Value ($000) $13,110 Avg Close $121.62 Range $95.11 - $169.76

Q1 2021

Shares 25,623 Value ($000) $3,122 Avg Close $151.00 Range $100.00 - $220.20

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2022	2,200	$89	$53.05	$38.94 - $66.31
Q2 2022	5,500	$334	$58.79	$42.51 - $75.42
Q3 2021	80,978	$9,064	$125.59	$109.63 - $163.00
Q2 2021	80,978	$13,110	$121.62	$95.11 - $169.76
Q1 2021	25,623	$3,122	$151.00	$100.00 - $220.20