CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

Aperio Group, LLC's Holding History (CIK: 0001364615)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020

Shares 2,838 Value ($000) $435 Avg Close $118.20 Range $79.31 - $181.42

Q1 2020

Shares 5,392 Value ($000) $229 Avg Close $51.63 Range $32.30 - $64.19

Q4 2019

Shares 4,471 Value ($000) $272 Avg Close $54.60 Range $35.46 - $74.00

Q2 2019

Shares 3,247 Value ($000) $153 Avg Close $39.97 Range $34.91 - $48.30

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2020	2,838	$435	$118.20	$79.31 - $181.42
Q1 2020	5,392	$229	$51.63	$32.30 - $64.19
Q4 2019	4,471	$272	$54.60	$35.46 - $74.00
Q2 2019	3,247	$153	$39.97	$34.91 - $48.30