CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

Twin Tree Management, LP's Holding History (CIK: 0001535588)

Note: Option positions (PUT/CALL) are excluded.

Q4 2023

Shares 39,772 Value ($000) $2,490 Avg Close $55.02 Range $37.55 - $76.97

Q4 2022

Shares 47,585 Value ($000) $1,934 Avg Close $53.05 Range $38.94 - $66.31

Q3 2022

Shares 127,524 Value ($000) $8,334 Avg Close $72.47 Range $60.41 - $86.95

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2023	39,772	$2,490	$55.02	$37.55 - $76.97
Q4 2022	47,585	$1,934	$53.05	$38.94 - $66.31
Q3 2022	127,524	$8,334	$72.47	$60.41 - $86.95