CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

Connor, Clark & Lunn Investment Management Ltd.'s Holding History (CIK: 0001596800)

Note: Option positions (PUT/CALL) are excluded.

Q3 2022

Shares 49,068 Value ($000) $3,207 Avg Close $72.47 Range $60.41 - $86.95

Q2 2022

Shares 12,211 Value ($000) $742 Avg Close $58.79 Range $42.51 - $75.42

Q1 2022

Shares 33,321 Value ($000) $2,092 Avg Close $62.79 Range $50.54 - $79.40

Q3 2021

Shares 116,485 Value ($000) $13,038 Avg Close $125.59 Range $109.63 - $163.00

Q2 2021

Shares 97,142 Value ($000) $15,726 Avg Close $121.62 Range $95.11 - $169.76

Q1 2021

Shares 5,143 Value ($000) $627 Avg Close $151.00 Range $100.00 - $220.20

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2022	49,068	$3,207	$72.47	$60.41 - $86.95
Q2 2022	12,211	$742	$58.79	$42.51 - $75.42
Q1 2022	33,321	$2,092	$62.79	$50.54 - $79.40
Q3 2021	116,485	$13,038	$125.59	$109.63 - $163.00
Q2 2021	97,142	$15,726	$121.62	$95.11 - $169.76
Q1 2021	5,143	$627	$151.00	$100.00 - $220.20