CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

BTC Capital Management, Inc.'s Holding History (CIK: 0001611848)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022

Shares 3,204 Value ($000) $200 Avg Close $62.79 Range $50.54 - $79.40

Q4 2021

Shares 2,767 Value ($000) $210 Avg Close $87.36 Range $67.15 - $112.39

Q2 2021

Shares 1,436 Value ($000) $233 Avg Close $121.62 Range $95.11 - $169.76

Q1 2021

Shares 1,837 Value ($000) $224 Avg Close $151.00 Range $100.00 - $220.20

Q4 2020

Shares 2,082 Value ($000) $317 Avg Close $118.20 Range $79.31 - $181.42

Q3 2018

Shares 5,485 Value ($000) $246 Avg Close $52.37 Range $43.68 - $66.26

Q2 2018

Shares 4,323 Value ($000) $258 Avg Close $56.97 Range $40.25 - $73.90

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2022	3,204	$200	$62.79	$50.54 - $79.40
Q4 2021	2,767	$210	$87.36	$67.15 - $112.39
Q2 2021	1,436	$233	$121.62	$95.11 - $169.76
Q1 2021	1,837	$224	$151.00	$100.00 - $220.20
Q4 2020	2,082	$317	$118.20	$79.31 - $181.42
Q3 2018	5,485	$246	$52.37	$43.68 - $66.26
Q2 2018	4,323	$258	$56.97	$40.25 - $73.90