CRISPR THERAPEUTICS AG

Ticker: CRSP CUSIP: H17182108 Class: NAMEN AKT

Vivo Capital, LLC's Holding History (CIK: 0001674712)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017

Shares 98,511 Value ($000) $2,313 Avg Close $19.00 Range $16.51 - $25.00

Q3 2017

Shares 148,878 Value ($000) $2,660 Avg Close $18.13 Range $15.55 - $21.32

Q2 2017

Shares 148,878 Value ($000) $2,385 Avg Close $16.52 Range $13.50 - $22.22

Q1 2017

Shares 148,878 Value ($000) $3,241 Avg Close $19.63 Range $11.63 - $25.00

Q4 2016

Shares 148,878 Value ($000) $3,016 Avg Close $18.69 Range $13.75 - $23.97

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2017	98,511	$2,313	$19.00	$16.51 - $25.00
Q3 2017	148,878	$2,660	$18.13	$15.55 - $21.32
Q2 2017	148,878	$2,385	$16.52	$13.50 - $22.22
Q1 2017	148,878	$3,241	$19.63	$11.63 - $25.00
Q4 2016	148,878	$3,016	$18.69	$13.75 - $23.97