SOPHIA GENETICS SA

Ticker: SOPH CUSIP: H82027105 Class: ORDINARY SHARES

RTW INVESTMENTS, LP's Holding History (CIK: 0001493215)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022

Shares 226,589 Value ($000) $1,752 Avg Close $11.23 Range $7.12 - $15.83

Q4 2021

Shares 300,000 Value ($000) $4,230 Avg Close $14.75 Range $11.71 - $19.19

Q3 2021

Shares 300,000 Value ($000) $5,259 Avg Close $17.59 Range $14.88 - $19.80

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2022	226,589	$1,752	$11.23	$7.12 - $15.83
Q4 2021	300,000	$4,230	$14.75	$11.71 - $19.19
Q3 2021	300,000	$5,259	$17.59	$14.88 - $19.80