ALCOBRA LTD

CUSIP: M2239P109 Class: SHS

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 200 Value ($000) $1 Avg Close — Range —
Q4 2014
Shares 38,500 Value ($000) $144 Avg Close — Range —