GALMED PHARMACEUTICALS LTD

Ticker: GLMD CUSIP: M47238148 Class: SHS

Holders for Q4 2025 Position Changes for Q4 2025

Note: Option positions (PUT/CALL) are excluded.

New Positions (5)

TWO SIGMA SECURITIES, LLC

Value ($000) $10 Shares 13,602

TWO SIGMA ADVISERS, LP

Value ($000) $24 Shares 31,491

Value ($000) $8 Shares 11,048

JANE STREET GROUP, LLC

Value ($000) $9 Shares 12,135

BNP PARIBAS ARBITRAGE, SA

Value ($000) $1 Shares 900

Institution	Shares	Value ($000)
TWO SIGMA SECURITIES, LLC	13,602	$10
TWO SIGMA ADVISERS, LP	31,491	$24
XTX Topco Ltd	11,048	$8
JANE STREET GROUP, LLC	12,135	$9
BNP PARIBAS ARBITRAGE, SA	900	$1

Increased Positions (3)

TWO SIGMA INVESTMENTS, LP

Value ($000) $84 (+187.7%) Shares 112,147 (+429.0%)

Value ($000) $1 (+2.3%) Shares 1,814 (+88.4%)

Value ($000) $0 (+65.9%) Shares 298 (+204.1%)

Institution	Prev Shares	Curr Shares	Change
TWO SIGMA INVESTMENTS, LP	21,200	112,147	+90,947 (+429.0%)
UBS Group AG	963	1,814	+851 (+88.4%)
MORGAN STANLEY	98	298	+200 (+204.1%)

Decreased Positions (1)

CITADEL ADVISORS LLC

Value ($000) $29 (-59.8%) Shares 38,177 (-24.4%)

Institution	Prev Shares	Curr Shares	Change
CITADEL ADVISORS LLC	50,492	38,177	-12,315 (-24.4%)

Exited Positions (2)

Wealthspire Advisors, LLC

Value ($000) $0 Shares 21

TD Waterhouse Canada Inc.

Value ($000) $0 Shares 2

Institution	Prev Shares	Prev Value ($000)
Wealthspire Advisors, LLC	21	$0
TD Waterhouse Canada Inc.	2	$0