UROGEN PHARMA LTD

Ticker: URGN CUSIP: M96088105 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 241,213 Value ($000) $5,649 Avg Close $21.69 Range $15.86 - $30.00

Q3 2025

Shares 386,203 Value ($000) $7,705 Avg Close $17.96 Range $12.73 - $21.71

Q2 2025

Shares 189,412 Value ($000) $2,595 Avg Close $9.60 Range $3.42 - $15.61

Q1 2025

Shares 17,288 Value ($000) $191 Avg Close $10.66 Range $9.03 - $12.37

Q4 2024

Shares 56,895 Value ($000) $606 Avg Close $11.97 Range $10.26 - $13.64

Q3 2024

Shares 87,034 Value ($000) $1,105 Avg Close $14.84 Range $12.60 - $18.15

Q2 2024

Shares 100,422 Value ($000) $1,685 Avg Close $14.22 Range $10.60 - $20.70

Q1 2024

Shares 80,497 Value ($000) $1,207 Avg Close $16.35 Range $13.40 - $19.87

Q4 2023

Shares 130,755 Value ($000) $1,961 Avg Close $12.98 Range $10.63 - $16.32

Q3 2023

Shares 120,214 Value ($000) $1,684 Avg Close $16.05 Range $8.69 - $24.13

Q2 2023

Shares 19,815 Value ($000) $205 Avg Close $11.03 Range $8.57 - $16.11

Q1 2021

Shares 19,800 Value ($000) $386 Avg Close $21.23 Range $17.54 - $28.20

Q3 2018

Shares 5,954 Value ($000) $281 Avg Close $46.47 Range $40.58 - $52.20

Q4 2017

Shares 7,436 Value ($000) $277 Avg Close $35.61 Range $25.56 - $44.63

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	241,213	$5,649	$21.69	$15.86 - $30.00
Q3 2025	386,203	$7,705	$17.96	$12.73 - $21.71
Q2 2025	189,412	$2,595	$9.60	$3.42 - $15.61
Q1 2025	17,288	$191	$10.66	$9.03 - $12.37
Q4 2024	56,895	$606	$11.97	$10.26 - $13.64
Q3 2024	87,034	$1,105	$14.84	$12.60 - $18.15
Q2 2024	100,422	$1,685	$14.22	$10.60 - $20.70
Q1 2024	80,497	$1,207	$16.35	$13.40 - $19.87
Q4 2023	130,755	$1,961	$12.98	$10.63 - $16.32
Q3 2023	120,214	$1,684	$16.05	$8.69 - $24.13
Q2 2023	19,815	$205	$11.03	$8.57 - $16.11
Q1 2021	19,800	$386	$21.23	$17.54 - $28.20
Q3 2018	5,954	$281	$46.47	$40.58 - $52.20
Q4 2017	7,436	$277	$35.61	$25.56 - $44.63