AFFIMED N V

CUSIP: N01045108 Class: Foreign Stock

Opaleye Management Inc.'s Holding History (CIK: 0001595855)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 430,000 Value ($000) $1,195 Avg Close — Range —
Q2 2016
Shares 595,000 Value ($000) $1,476 Avg Close — Range —
Q1 2016
Shares 610,000 Value ($000) $2,281 Avg Close — Range —
Q4 2015
Shares 595,000 Value ($000) $4,236 Avg Close — Range —
Q3 2015
Shares 590,300 Value ($000) $3,642 Avg Close — Range —
Q2 2015
Shares 590,300 Value ($000) $7,951 Avg Close — Range —