PROQR THRAPEUTICS N V

Ticker: PRQR CUSIP: N71542109 Class: SHS EURO

JGP Global Gestao de Recursos Ltda.'s Holding History (CIK: 0001536562)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 16,433 Value ($000) $228 Avg Close $14.93 Range $12.25 - $18.94

Q4 2018

Shares 14,870 Value ($000) $235 Avg Close $18.36 Range $14.83 - $24.00

Q3 2018

Shares 15,618 Value ($000) $302 Avg Close $10.63 Range $6.25 - $22.85

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	16,433	$228	$14.93	$12.25 - $18.94
Q4 2018	14,870	$235	$18.36	$14.83 - $24.00
Q3 2018	15,618	$302	$10.63	$6.25 - $22.85