UNIQURE NV

Ticker: QURE CUSIP: N90064101 Class: Common Stock

FRED ALGER MANAGEMENT, LLC's Holding History (CIK: 0000003520)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 344,878 Value ($000) $8,253 Avg Close $38.59 Range $19.29 - $71.50

Q3 2025

Shares 1,290,391 Value ($000) $75,320 Avg Close $18.16 Range $12.33 - $60.70

Q4 2019

Shares 7,000 Value ($000) $502 Avg Close $54.91 Range $36.20 - $76.09

Q2 2019

Shares 10,500 Value ($000) $821 Avg Close $63.72 Range $51.85 - $82.49

Q2 2018

Shares 26,000 Value ($000) $983 Avg Close $32.02 Range $21.57 - $40.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	344,878	$8,253	$38.59	$19.29 - $71.50
Q3 2025	1,290,391	$75,320	$18.16	$12.33 - $60.70
Q4 2019	7,000	$502	$54.91	$36.20 - $76.09
Q2 2019	10,500	$821	$63.72	$51.85 - $82.49
Q2 2018	26,000	$983	$32.02	$21.57 - $40.98