UNIQURE NV

Ticker: QURE CUSIP: N90064101 Class: Common Stock

Jefferies Financial Group Inc.'s Holding History (CIK: 0000096223)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 90,542 Value ($000) $2,167 Avg Close $38.59 Range $19.29 - $71.50

Q3 2025

Shares 90,542 Value ($000) $5,285 Avg Close $18.16 Range $12.33 - $60.70

Q2 2025

Shares 2,095,931 Value ($000) $29,217 Avg Close $13.45 Range $7.76 - $17.60

Q2 2023

Shares 25,000 Value ($000) $287 Avg Close $18.95 Range $10.51 - $22.48

Q4 2022

Shares 14,750 Value ($000) $334 Avg Close $21.57 Range $17.85 - $28.25

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	90,542	$2,167	$38.59	$19.29 - $71.50
Q3 2025	90,542	$5,285	$18.16	$12.33 - $60.70
Q2 2025	2,095,931	$29,217	$13.45	$7.76 - $17.60
Q2 2023	25,000	$287	$18.95	$10.51 - $22.48
Q4 2022	14,750	$334	$21.57	$17.85 - $28.25