UNIQURE NV

Ticker: QURE CUSIP: N90064101 Class: Common Stock

Artal Group S.A.'s Holding History (CIK: 0001053906)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020

Shares 700,000 Value ($000) $25,291 Avg Close $42.18 Range $34.38 - $52.19

Q3 2020

Shares 750,000 Value ($000) $27,623 Avg Close $40.97 Range $35.76 - $48.50

Q2 2020

Shares 1,000,000 Value ($000) $45,060 Avg Close $59.06 Range $44.63 - $71.45

Q1 2020

Shares 1,150,000 Value ($000) $54,568 Avg Close $57.46 Range $37.50 - $76.69

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2020	700,000	$25,291	$42.18	$34.38 - $52.19
Q3 2020	750,000	$27,623	$40.97	$35.76 - $48.50
Q2 2020	1,000,000	$45,060	$59.06	$44.63 - $71.45
Q1 2020	1,150,000	$54,568	$57.46	$37.50 - $76.69