UNIQURE NV

Ticker: QURE CUSIP: N90064101 Class: Common Stock

CAPITAL FUND MANAGEMENT S.A.'s Holding History (CIK: 0001323645)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 82,978 Value ($000) $1,986 Avg Close $38.59 Range $19.29 - $71.50

Q3 2020

Shares 14,499 Value ($000) $533,998 Avg Close $40.97 Range $35.76 - $48.50

Q2 2020

Shares 14,472 Value ($000) $652,108 Avg Close $59.06 Range $44.63 - $71.45

Q1 2020

Shares 6,100 Value ($000) $289 Avg Close $57.46 Range $37.50 - $76.69

Q4 2019

Shares 3,877 Value ($000) $278 Avg Close $54.91 Range $36.20 - $76.09

Q3 2016

Shares 14,500 Value ($000) $111 Avg Close $7.93 Range $6.68 - $9.72

Q1 2016

Shares 42,795 Value ($000) $508 Avg Close $14.77 Range $10.61 - $19.40

Q4 2015

Shares 11,200 Value ($000) $185 Avg Close $18.53 Range $15.05 - $22.93

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	82,978	$1,986	$38.59	$19.29 - $71.50
Q3 2020	14,499	$533,998	$40.97	$35.76 - $48.50
Q2 2020	14,472	$652,108	$59.06	$44.63 - $71.45
Q1 2020	6,100	$289	$57.46	$37.50 - $76.69
Q4 2019	3,877	$278	$54.91	$36.20 - $76.09
Q3 2016	14,500	$111	$7.93	$6.68 - $9.72
Q1 2016	42,795	$508	$14.77	$10.61 - $19.40
Q4 2015	11,200	$185	$18.53	$15.05 - $22.93