UNIQURE NV

Ticker: QURE CUSIP: N90064101 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016

Shares 15,479 Value ($000) $87 Avg Close $6.71 Range $5.45 - $8.32

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2016	15,479	$87	$6.71	$5.45 - $8.32