UNIQURE NV

Ticker: QURE CUSIP: N90064101 Class: Common Stock

Swiss National Bank's Holding History (CIK: 0001582202)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 79,000 Value ($000) $1,890 Avg Close $38.59 Range $19.29 - $71.50

Q3 2025

Shares 76,300 Value ($000) $4,454 Avg Close $18.16 Range $12.33 - $60.70

Q2 2025

Shares 77,500 Value ($000) $1,080 Avg Close $13.45 Range $7.76 - $17.60

Q3 2023

Shares 99,400 Value ($000) $667 Avg Close $9.00 Range $6.64 - $11.95

Q2 2023

Shares 92,000 Value ($000) $1,054 Avg Close $18.95 Range $10.51 - $22.48

Q1 2023

Shares 91,000 Value ($000) $1,833 Avg Close $20.98 Range $18.01 - $23.46

Q4 2022

Shares 101,500 Value ($000) $2,301 Avg Close $21.57 Range $17.85 - $28.25

Q3 2022

Shares 99,600 Value ($000) $1,868 Avg Close $21.02 Range $16.75 - $25.81

Q2 2022

Shares 98,000 Value ($000) $1,827 Avg Close $15.91 Range $12.52 - $20.72

Q1 2022

Shares 82,000 Value ($000) $1,482 Avg Close $17.46 Range $14.29 - $21.85

Q4 2021

Shares 76,300 Value ($000) $1,582 Avg Close $28.68 Range $19.50 - $36.55

Q3 2021

Shares 76,300 Value ($000) $2,442 Avg Close $30.48 Range $25.80 - $38.80

Q2 2021

Shares 73,600 Value ($000) $2,267 Avg Close $33.51 Range $29.85 - $37.78

Q1 2021

Shares 76,300 Value ($000) $2,571 Avg Close $35.84 Range $28.58 - $42.27

Q4 2020

Shares 75,300 Value ($000) $2,721 Avg Close $42.18 Range $34.38 - $52.19

Q3 2020

Shares 75,300 Value ($000) $2,773 Avg Close $40.97 Range $35.76 - $48.50

Q2 2020

Shares 73,100 Value ($000) $3,294 Avg Close $59.06 Range $44.63 - $71.45

Q1 2020

Shares 67,700 Value ($000) $3,212 Avg Close $57.46 Range $37.50 - $76.69

Q4 2019

Shares 65,500 Value ($000) $4,694 Avg Close $54.91 Range $36.20 - $76.09

Q3 2019

Shares 64,100 Value ($000) $2,523 Avg Close $57.69 Range $38.07 - $77.46

Q2 2019

Shares 52,500 Value ($000) $4,103 Avg Close $63.72 Range $51.85 - $82.49

Q1 2019

Shares 44,200 Value ($000) $2,637 Avg Close $44.67 Range $26.94 - $69.60

Q4 2018

Shares 42,700 Value ($000) $1,231 Avg Close $27.83 Range $21.98 - $37.30

Q3 2018

Shares 41,000 Value ($000) $1,492 Avg Close $37.20 Range $28.00 - $43.23

Q2 2018

Shares 41,000 Value ($000) $1,550 Avg Close $32.02 Range $21.57 - $40.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	79,000	$1,890	$38.59	$19.29 - $71.50
Q3 2025	76,300	$4,454	$18.16	$12.33 - $60.70
Q2 2025	77,500	$1,080	$13.45	$7.76 - $17.60
Q3 2023	99,400	$667	$9.00	$6.64 - $11.95
Q2 2023	92,000	$1,054	$18.95	$10.51 - $22.48
Q1 2023	91,000	$1,833	$20.98	$18.01 - $23.46
Q4 2022	101,500	$2,301	$21.57	$17.85 - $28.25
Q3 2022	99,600	$1,868	$21.02	$16.75 - $25.81
Q2 2022	98,000	$1,827	$15.91	$12.52 - $20.72
Q1 2022	82,000	$1,482	$17.46	$14.29 - $21.85
Q4 2021	76,300	$1,582	$28.68	$19.50 - $36.55
Q3 2021	76,300	$2,442	$30.48	$25.80 - $38.80
Q2 2021	73,600	$2,267	$33.51	$29.85 - $37.78
Q1 2021	76,300	$2,571	$35.84	$28.58 - $42.27
Q4 2020	75,300	$2,721	$42.18	$34.38 - $52.19
Q3 2020	75,300	$2,773	$40.97	$35.76 - $48.50
Q2 2020	73,100	$3,294	$59.06	$44.63 - $71.45
Q1 2020	67,700	$3,212	$57.46	$37.50 - $76.69
Q4 2019	65,500	$4,694	$54.91	$36.20 - $76.09
Q3 2019	64,100	$2,523	$57.69	$38.07 - $77.46
Q2 2019	52,500	$4,103	$63.72	$51.85 - $82.49
Q1 2019	44,200	$2,637	$44.67	$26.94 - $69.60
Q4 2018	42,700	$1,231	$27.83	$21.98 - $37.30
Q3 2018	41,000	$1,492	$37.20	$28.00 - $43.23
Q2 2018	41,000	$1,550	$32.02	$21.57 - $40.98