UNIQURE NV

Ticker: QURE CUSIP: N90064101 Class: Common Stock

Polar Capital Holdings Plc's Holding History (CIK: 0001837309)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 13,200 Value ($000) $274 Avg Close $28.68 Range $19.50 - $36.55

Q3 2021

Shares 33,476 Value ($000) $1,072 Avg Close $30.48 Range $25.80 - $38.80

Q2 2021

Shares 33,476 Value ($000) $1,031 Avg Close $33.51 Range $29.85 - $37.78

Q1 2021

Shares 22,031 Value ($000) $742 Avg Close $35.84 Range $28.58 - $42.27

Q4 2020

Shares 22,031 Value ($000) $796 Avg Close $42.18 Range $34.38 - $52.19

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	13,200	$274	$28.68	$19.50 - $36.55
Q3 2021	33,476	$1,072	$30.48	$25.80 - $38.80
Q2 2021	33,476	$1,031	$33.51	$29.85 - $37.78
Q1 2021	22,031	$742	$35.84	$28.58 - $42.27
Q4 2020	22,031	$796	$42.18	$34.38 - $52.19