WAVE LIFE SCIENCES LTD

Ticker: WVE CUSIP: Y95308105 Class: Common Stock

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 266,132 Value ($000) $4,524 Avg Close $10.16 Range $6.51 - $21.73

Q2 2025

Shares 271,474 Value ($000) $1,765 Avg Close $6.60 Range $5.28 - $8.39

Q1 2025

Shares 106,554 Value ($000) $861 Avg Close $10.94 Range $7.92 - $13.92

Q4 2024

Shares 716,253 Value ($000) $8,860 Avg Close $13.35 Range $7.85 - $16.74

Q3 2024

Shares 418,461 Value ($000) $3,431 Avg Close $5.98 Range $4.87 - $9.92

Q2 2024

Shares 108,567 Value ($000) $542 Avg Close $5.70 Range $4.25 - $6.63

Q1 2024

Shares 285,092 Value ($000) $1,759 Avg Close $5.01 Range $3.50 - $7.67

Q3 2022

Shares 307,175 Value ($000) $1,109 Avg Close $3.31 Range $2.32 - $4.64

Q2 2022

Shares 940,465 Value ($000) $3,056 Avg Close $1.92 Range $1.16 - $3.57

Q1 2022

Shares 1,091,300 Value ($000) $2,182 Avg Close $2.45 Range $1.92 - $3.40

Q4 2021

Shares 1,110,289 Value ($000) $3,486 Avg Close $4.15 Range $3.07 - $5.22

Q3 2021

Shares 1,101,650 Value ($000) $5,398 Avg Close $6.06 Range $4.87 - $7.24

Q2 2021

Shares 1,255,560 Value ($000) $8,362 Avg Close $6.53 Range $5.46 - $7.55

Q1 2021

Shares 1,262,109 Value ($000) $7,080 Avg Close $9.61 Range $4.82 - $12.17

Q4 2020

Shares 1,499,259 Value ($000) $11,799 Avg Close $8.39 Range $6.76 - $9.73

Q3 2020

Shares 706,415 Value ($000) $5,997 Avg Close $10.96 Range $8.17 - $19.98

Q2 2020

Shares 561,961 Value ($000) $5,850 Avg Close $9.41 Range $7.40 - $11.79

Q1 2020

Shares 32,112 Value ($000) $301 Avg Close $8.52 Range $6.61 - $17.24

Q4 2019

Shares 22,548 Value ($000) $181 Avg Close $24.52 Range $7.78 - $39.98

Q3 2019

Shares 18,690 Value ($000) $384 Avg Close $22.93 Range $18.16 - $28.12

Q2 2019

Shares 85,979 Value ($000) $2,243 Avg Close $28.04 Range $22.25 - $43.00

Q1 2019

Shares 242,644 Value ($000) $9,427 Avg Close $40.58 Range $32.51 - $48.64

Q4 2018

Shares 125,291 Value ($000) $5,268 Avg Close $44.47 Range $34.38 - $51.68

Q3 2018

Shares 109,114 Value ($000) $5,455 Avg Close $45.12 Range $35.35 - $56.00

Q2 2018

Shares 77,972 Value ($000) $2,982 Avg Close $43.05 Range $32.25 - $50.88

Q1 2018

Shares 57,052 Value ($000) $2,288 Avg Close $42.04 Range $31.65 - $55.95

Q4 2017

Shares 6,442 Value ($000) $226 Avg Close $29.15 Range $21.00 - $39.70

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	266,132	$4,524	$10.16	$6.51 - $21.73
Q2 2025	271,474	$1,765	$6.60	$5.28 - $8.39
Q1 2025	106,554	$861	$10.94	$7.92 - $13.92
Q4 2024	716,253	$8,860	$13.35	$7.85 - $16.74
Q3 2024	418,461	$3,431	$5.98	$4.87 - $9.92
Q2 2024	108,567	$542	$5.70	$4.25 - $6.63
Q1 2024	285,092	$1,759	$5.01	$3.50 - $7.67
Q3 2022	307,175	$1,109	$3.31	$2.32 - $4.64
Q2 2022	940,465	$3,056	$1.92	$1.16 - $3.57
Q1 2022	1,091,300	$2,182	$2.45	$1.92 - $3.40
Q4 2021	1,110,289	$3,486	$4.15	$3.07 - $5.22
Q3 2021	1,101,650	$5,398	$6.06	$4.87 - $7.24
Q2 2021	1,255,560	$8,362	$6.53	$5.46 - $7.55
Q1 2021	1,262,109	$7,080	$9.61	$4.82 - $12.17
Q4 2020	1,499,259	$11,799	$8.39	$6.76 - $9.73
Q3 2020	706,415	$5,997	$10.96	$8.17 - $19.98
Q2 2020	561,961	$5,850	$9.41	$7.40 - $11.79
Q1 2020	32,112	$301	$8.52	$6.61 - $17.24
Q4 2019	22,548	$181	$24.52	$7.78 - $39.98
Q3 2019	18,690	$384	$22.93	$18.16 - $28.12
Q2 2019	85,979	$2,243	$28.04	$22.25 - $43.00
Q1 2019	242,644	$9,427	$40.58	$32.51 - $48.64
Q4 2018	125,291	$5,268	$44.47	$34.38 - $51.68
Q3 2018	109,114	$5,455	$45.12	$35.35 - $56.00
Q2 2018	77,972	$2,982	$43.05	$32.25 - $50.88
Q1 2018	57,052	$2,288	$42.04	$31.65 - $55.95
Q4 2017	6,442	$226	$29.15	$21.00 - $39.70