WAVE LIFE SCIENCES LTD

Ticker: WVE CUSIP: Y95308105 Class: Common Stock

Itau Unibanco Holding S.A.'s Holding History (CIK: 0001132597)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 102,000 Value ($000) $1,749 Avg Close $10.16 Range $6.51 - $21.73

Q3 2019

Shares 487 Value ($000) $13 Avg Close $22.93 Range $18.16 - $28.12

Q2 2019

Shares 487 Value ($000) $13 Avg Close $28.04 Range $22.25 - $43.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	102,000	$1,749	$10.16	$6.51 - $21.73
Q3 2019	487	$13	$22.93	$18.16 - $28.12
Q2 2019	487	$13	$28.04	$22.25 - $43.00