RTW INVESTMENTS, LP Diversified Active

CIK: 0001493215 · Show all filings

Period: Q4 2014 (Next →)

Filing Date: Feb 17, 2015

Total Value ($000): $270,288 (100.0% shares, 0.0% debt)

Holdings (21)

— TARO PHARMACEUTICAL INDS LTD 14.7%

Value ($000) $39,698 Shares 267,883 Est. Cost $148.19 Unrealized —

ALNY ALNYLAM PHARMACEUTICALS INC 12.2%

Value ($000) $33,018 Shares 340,395 Est. Cost $92.65 Unrealized 0.0%

— DYAX CORP 11.1%

Value ($000) $29,973 Shares 2,131,808 Est. Cost $14.06 Unrealized —

BCRX BIOCRYST PHARMACEUTICALS 10.2%

Value ($000) $27,498 Shares 2,261,361 Est. Cost $11.05 Unrealized 0.0%

— ACHILLION PHARMACEUTICALS IN 7.4%

Value ($000) $19,877 Shares 1,622,633 Est. Cost $12.25 Unrealized —

— LA JOLLA PHARMACEUTICAL CO 7.3%

Value ($000) $19,635 Shares 1,064,247 Est. Cost $18.45 Unrealized —

— ARROWHEAD RESH CORP 7.1%

Value ($000) $19,262 Shares 2,610,000 Est. Cost $7.38 Unrealized —

— DICERNA PHARMACEUTICALS INC 6.8%

Value ($000) $18,380 Shares 1,115,981 Est. Cost $16.47 Unrealized —

— ZS PHARMA INC 5.8%

Value ($000) $15,581 Shares 374,821 Est. Cost $41.57 Unrealized —

— RELYPSA INC 5.1%

Value ($000) $13,867 Shares 450,239 Est. Cost $30.80 Unrealized —

— XENOPORT INC 2.7%

Value ($000) $7,389 Shares 842,568 Est. Cost $8.77 Unrealized —

VNDA VANDA PHARMACEUTICALS INC 2.6%

Value ($000) $7,160 Shares 500,000 Est. Cost $11.83 Unrealized 0.0%

— TARGACEPT INC 2.6%

Value ($000) $7,011 Shares 2,665,643 Est. Cost $2.63 Unrealized —

— AVALANCHE BIOTECHNOLOGIES IN 1.0%

Value ($000) $2,700 Shares 50,000 Est. Cost $54.00 Unrealized —

— REPROS THERAPEUTICS INC 0.8%

Value ($000) $2,287 Shares 229,364 Est. Cost $9.97 Unrealized —

— CYTRX CORP 0.7%

Value ($000) $1,932 Shares 705,000 Est. Cost $2.74 Unrealized —

— ASSEMBLY BIOSCIENCES INC 0.6%

Value ($000) $1,603 Shares 204,000 Est. Cost $7.86 Unrealized —

— PROTALIX BIOTHERAPEUTICS INC 0.6%

Value ($000) $1,553 Shares 843,851 Est. Cost $1.84 Unrealized —

— LIPOCINE INC NEW 0.4%

Value ($000) $1,101 Shares 209,333 Est. Cost $5.26 Unrealized —

— NEVRO CORP 0.2%

Value ($000) $594 Shares 15,356 Est. Cost $38.68 Unrealized —

— LPATH INC 0.1%

Value ($000) $169 Shares 60,000 Est. Cost $2.82 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
—	TARO PHARMACEUTICAL INDS LTD	267,883	$39,698	14.7%	$148.19	—	SHS	M8737E108
ALNY	ALNYLAM PHARMACEUTICALS INC	340,395	$33,018	12.2%	$92.65	0.0%	COM	02043Q107
—	DYAX CORP	2,131,808	$29,973	11.1%	$14.06	—	COM	26746E103
BCRX	BIOCRYST PHARMACEUTICALS	2,261,361	$27,498	10.2%	$11.05	0.0%	COM	09058V103
—	ACHILLION PHARMACEUTICALS IN	1,622,633	$19,877	7.4%	$12.25	—	COM	00448Q201
—	LA JOLLA PHARMACEUTICAL CO	1,064,247	$19,635	7.3%	$18.45	—	COM PAR $.0001 2	503459604
—	ARROWHEAD RESH CORP	2,610,000	$19,262	7.1%	$7.38	—	COM NEW	042797209
—	DICERNA PHARMACEUTICALS INC	1,115,981	$18,380	6.8%	$16.47	—	COM	253031108
—	ZS PHARMA INC	374,821	$15,581	5.8%	$41.57	—	COM	98979G105
—	RELYPSA INC	450,239	$13,867	5.1%	$30.80	—	COM	759531106
—	XENOPORT INC	842,568	$7,389	2.7%	$8.77	—	COM	98411C100
VNDA	VANDA PHARMACEUTICALS INC	500,000	$7,160	2.6%	$11.83	0.0%	COM	921659108
—	TARGACEPT INC	2,665,643	$7,011	2.6%	$2.63	—	COM	87611R306
—	AVALANCHE BIOTECHNOLOGIES IN	50,000	$2,700	1.0%	$54.00	—	COM	05337G107
—	REPROS THERAPEUTICS INC	229,364	$2,287	0.8%	$9.97	—	COM NEW	76028H209
—	CYTRX CORP	705,000	$1,932	0.7%	$2.74	—	COM PAR $.001	232828509
—	ASSEMBLY BIOSCIENCES INC	204,000	$1,603	0.6%	$7.86	—	COM	045396108
—	PROTALIX BIOTHERAPEUTICS INC	843,851	$1,553	0.6%	$1.84	—	COM	74365A101
—	LIPOCINE INC NEW	209,333	$1,101	0.4%	$5.26	—	COM	53630X104
—	NEVRO CORP	15,356	$594	0.2%	$38.68	—	COM	64157F103
—	LPATH INC	60,000	$169	0.1%	$2.82	—	COM NEW	548910306