Casdin Capital, LLC Diversified Active

Location: New York, NY

CIK: 0001534261 · Show all filings

Period: Q2 2025 (← Previous) (Next →)

Filing Date: Aug 14, 2025

Total Value: $1.098B (100.0% shares, 0.0% debt)

Holdings (33)

WGS GENEDX HOLDINGS CORP 29.5%

Value $324M Shares 3,507,164 Est. Cost $9.11 Unrealized +761.4%

BLFS BIOLIFE SOLUTIONS INC 15.1%

Value $166M Shares 7,707,165 Est. Cost $19.43 Unrealized +16.0%

RVMD REVOLUTION MEDICINES INC 9.7%

Value $106M Shares 2,887,933 Est. Cost $25.89 Unrealized +48.4%

LAB STANDARD BIOTOOLS INC 8.3%

Value $91.29M Shares 76,075,636 Est. Cost $2.30 Unrealized -51.8%

ILMN ILLUMINA INC 5.6%

Value $61.54M Shares 645,000 Est. Cost $116.47 Unrealized -30.3%

RNAM AVIDITY BIOSCIENCES INC 4.6%

Value $50.41M Shares 1,775,000 Est. Cost $14.11 Unrealized +111.3%

— VERVE THERAPEUTICS INC 4.2%

Value $45.99M Shares 4,095,571 Est. Cost $35.40 Unrealized —

RLAY RELAY THERAPEUTICS INC 3.6%

Value $39.44M Shares 11,398,574 Est. Cost $16.30 Unrealized -81.8%

ALNY ALNYLAM PHARMACEUTICALS INC 2.4%

Value $26.58M Shares 81,500 Est. Cost $138.08 Unrealized +100.4%

GPCR STRUCTURE THERAPEUTICS INC 2.3%

Value $25.41M Shares 1,225,000 Est. Cost $28.20 Unrealized —

BEAM BEAM THERAPEUTICS INC 2.2%

Value $24.66M Shares 1,450,000 Est. Cost $38.19 Unrealized -54.4%

NGNE NEUROGENE INC 1.8%

Value $19.37M Shares 1,295,361 Est. Cost $27.94 Unrealized -43.8%

CDXS CODEXIS INC 1.6%

Value $17.57M Shares 7,200,000 Est. Cost $2.87 Unrealized -18.2%

SRPT SAREPTA THERAPEUTICS INC 1.5%

Value $16.93M Shares 990,097 Est. Cost $95.60 Unrealized -55.4%

DNLI DENALI THERAPEUTICS INC 1.1%

Value $12.45M Shares 890,000 Est. Cost $29.48 Unrealized -52.3%

HIMS HIMS & HERS HEALTH INC 1.0%

Value $11.47M Shares 230,000 Est. Cost $38.20 Unrealized +18.3%

MAZE MAZE THERAPEUTICS INC 0.8%

Value $9.311M Shares 758,857 Est. Cost $12.04 Unrealized -13.6%

VCYT VERACYTE INC 0.7%

Value $7.469M Shares 276,308 Est. Cost $24.40 Unrealized +18.7%

LLY ELI LILLY & CO 0.6%

Value $6.626M Shares 8,500 Est. Cost $773.40 Unrealized 0.0%

SNDX SYNDAX PHARMACEUTICALS INC 0.6%

Value $6.084M Shares 650,000 Est. Cost $17.60 Unrealized -37.5%

SEPN SEPTERNA INC 0.5%

Value $5.848M Shares 553,268 Est. Cost $23.65 Unrealized -65.2%

GH GUARDANT HEALTH INC 0.5%

Value $5.204M Shares 100,000 Est. Cost $26.87 Unrealized +66.2%

EXAS EXACT SCIENCES CORP 0.4%

Value $4.783M Shares 90,000 Est. Cost $74.77 Unrealized -32.1%

PRME PRIME MEDICINE INC 0.4%

Value $3.871M Shares 1,567,175 Est. Cost $5.41 Unrealized -71.5%

AGIO AGIOS PHARMACEUTICALS INC 0.3%

Value $3.326M Shares 100,000 Est. Cost $46.98 Unrealized -35.5%

ABSI ABSCI CORPORATION 0.2%

Value $2.501M Shares 973,260 Est. Cost $19.41 Unrealized -85.5%

PACB PACIFIC BIOSCIENCES CALIF IN 0.1%

Value $897K Shares 723,767 Est. Cost $11.43 Unrealized -89.9%

RXRX RECURSION PHARMACEUTICALS IN 0.1%

Value $837K Shares 165,323 Est. Cost $6.72 Unrealized -26.9%

IPSC CENTURY THERAPEUTICS INC 0.1%

Value $686K Shares 1,228,190 Est. Cost $10.97 Unrealized -95.1%

CTNM CONTINEUM THERAPEUTICS INC 0.1%

Value $589K Shares 148,333 Est. Cost $16.10 Unrealized -73.0%

DNA GINKGO BIOWORKS HOLDINGS INC 0.0%

Value $411K Shares 36,493 Est. Cost $10.02 Unrealized -22.7%

GLUE MONTE ROSA THERAPEUTICS INC 0.0%

Value $388K Shares 86,014 Est. Cost $20.37 Unrealized -78.1%

TNYA TENAYA THERAPEUTICS INC 0.0%

Value $221K Shares 361,969 Est. Cost $12.86 Unrealized -96.0%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
WGS	GENEDX HOLDINGS CORP	3,507,164	$324M	29.5%	$9.11	+761.4%	COM CL A	81663L200
BLFS	BIOLIFE SOLUTIONS INC	7,707,165	$166M	15.1%	$19.43	+16.0%	COM NEW	09062W204
RVMD	REVOLUTION MEDICINES INC	2,887,933	$106M	9.7%	$25.89	+48.4%	COM	76155X100
LAB	STANDARD BIOTOOLS INC	76,075,636	$91.29M	8.3%	$2.30	-51.8%	COM	34385P108
ILMN	ILLUMINA INC	645,000	$61.54M	5.6%	$116.47	-30.3%	COM	452327109
RNAM	AVIDITY BIOSCIENCES INC	1,775,000	$50.41M	4.6%	$14.11	+111.3%	COM	05370A108
—	VERVE THERAPEUTICS INC	4,095,571	$45.99M	4.2%	$35.40	—	COM	92539P101
RLAY	RELAY THERAPEUTICS INC	11,398,574	$39.44M	3.6%	$16.30	-81.8%	COM	75943R102
ALNY	ALNYLAM PHARMACEUTICALS INC	81,500	$26.58M	2.4%	$138.08	+100.4%	COM	02043Q107
GPCR	STRUCTURE THERAPEUTICS INC	1,225,000	$25.41M	2.3%	$28.20	—	SPONSORED ADS	86366E106
BEAM	BEAM THERAPEUTICS INC	1,450,000	$24.66M	2.2%	$38.19	-54.4%	COM	07373V105
NGNE	NEUROGENE INC	1,295,361	$19.37M	1.8%	$27.94	-43.8%	COM	64135M105
CDXS	CODEXIS INC	7,200,000	$17.57M	1.6%	$2.87	-18.2%	COM	192005106
SRPT	SAREPTA THERAPEUTICS INC	990,097	$16.93M	1.5%	$95.60	-55.4%	COM	803607100
DNLI	DENALI THERAPEUTICS INC	890,000	$12.45M	1.1%	$29.48	-52.3%	COM	24823R105
HIMS	HIMS & HERS HEALTH INC	230,000	$11.47M	1.0%	$38.20	+18.3%	COM CL A	433000106
MAZE	MAZE THERAPEUTICS INC	758,857	$9.311M	0.8%	$12.04	-13.6%	COM	578784100
VCYT	VERACYTE INC	276,308	$7.469M	0.7%	$24.40	+18.7%	COM	92337F107
LLY	ELI LILLY & CO	8,500	$6.626M	0.6%	$773.40	0.0%	COM	532457108
SNDX	SYNDAX PHARMACEUTICALS INC	650,000	$6.084M	0.6%	$17.60	-37.5%	COM	87164F105
SEPN	SEPTERNA INC	553,268	$5.848M	0.5%	$23.65	-65.2%	COM	81734D104
GH	GUARDANT HEALTH INC	100,000	$5.204M	0.5%	$26.87	+66.2%	COM	40131M109
EXAS	EXACT SCIENCES CORP	90,000	$4.783M	0.4%	$74.77	-32.1%	COM	30063P105
PRME	PRIME MEDICINE INC	1,567,175	$3.871M	0.4%	$5.41	-71.5%	COM	74168J101
AGIO	AGIOS PHARMACEUTICALS INC	100,000	$3.326M	0.3%	$46.98	-35.5%	COM	00847X104
ABSI	ABSCI CORPORATION	973,260	$2.501M	0.2%	$19.41	-85.5%	COM	00091E109
PACB	PACIFIC BIOSCIENCES CALIF IN	723,767	$897K	0.1%	$11.43	-89.9%	COM	69404D108
RXRX	RECURSION PHARMACEUTICALS IN	165,323	$837K	0.1%	$6.72	-26.9%	CL A	75629V104
IPSC	CENTURY THERAPEUTICS INC	1,228,190	$686K	0.1%	$10.97	-95.1%	COM	15673T100
CTNM	CONTINEUM THERAPEUTICS INC	148,333	$589K	0.1%	$16.10	-73.0%	CL A	21217B100
DNA	GINKGO BIOWORKS HOLDINGS INC	36,493	$411K	0.0%	$10.02	-22.7%	CL A NEW	37611X209
GLUE	MONTE ROSA THERAPEUTICS INC	86,014	$388K	0.0%	$20.37	-78.1%	COM	61225M102
TNYA	TENAYA THERAPEUTICS INC	361,969	$221K	0.0%	$12.86	-96.0%	COM	87990A106