Casdin Capital, LLC Diversified Active

Location: New York, NY

CIK: 0001534261 · Show all filings

Period: Q3 2025 (← Previous) (Next →)

Filing Date: Nov 14, 2025

Total Value: $1.199B (100.0% shares, 0.0% debt)

Holdings (32)

WGS GENEDX HOLDINGS CORP 27.0%

Value $324M Shares 3,007,164 Est. Cost $9.11 Unrealized +1095.5%

BLFS BIOLIFE SOLUTIONS INC 14.3%

Value $171M Shares 6,707,165 Est. Cost $19.43 Unrealized +22.1%

RVMD REVOLUTION MEDICINES INC 10.3%

Value $124M Shares 2,647,333 Est. Cost $25.89 Unrealized +51.2%

LAB STANDARD BIOTOOLS INC 8.4%

Value $101M Shares 77,558,856 Est. Cost $2.28 Unrealized -42.6%

RNAM AVIDITY BIOSCIENCES INC 6.5%

Value $77.55M Shares 1,780,000 Est. Cost $14.11 Unrealized +186.6%

RLAY RELAY THERAPEUTICS INC 4.9%

Value $59.2M Shares 11,341,381 Est. Cost $16.30 Unrealized -76.6%

ILMN ILLUMINA INC 4.2%

Value $49.86M Shares 525,000 Est. Cost $116.47 Unrealized -14.8%

GPCR STRUCTURE THERAPEUTICS INC 3.6%

Value $43.54M Shares 1,555,000 Est. Cost $28.16 Unrealized —

BEAM BEAM THERAPEUTICS INC 3.2%

Value $38.83M Shares 1,600,000 Est. Cost $36.48 Unrealized -45.5%

ALNY ALNYLAM PHARMACEUTICALS INC 2.1%

Value $25.08M Shares 55,000 Est. Cost $138.08 Unrealized +194.9%

TEM TEMPUS AI INC 2.0%

Value $23.74M Shares 294,127 Est. Cost $70.04 Unrealized 0.0%

NGNE NEUROGENE INC 1.9%

Value $22.45M Shares 1,295,361 Est. Cost $27.94 Unrealized -28.1%

MAZE MAZE THERAPEUTICS INC 1.6%

Value $19.68M Shares 758,857 Est. Cost $12.04 Unrealized +40.2%

PRME PRIME MEDICINE INC 1.5%

Value $17.55M Shares 3,167,175 Est. Cost $4.73 Unrealized -14.1%

SPRY ARS PHARMACEUTICALS INC 1.3%

Value $16.08M Shares 1,600,000 Est. Cost $14.35 Unrealized 0.0%

HIMS HIMS & HERS HEALTH INC 1.1%

Value $13.05M Shares 230,000 Est. Cost $38.20 Unrealized +34.1%

DNLI DENALI THERAPEUTICS INC 1.1%

Value $12.92M Shares 890,000 Est. Cost $29.48 Unrealized -51.3%

SEPN SEPTERNA INC 0.9%

Value $10.41M Shares 553,268 Est. Cost $23.65 Unrealized -44.5%

VCYT VERACYTE INC 0.8%

Value $9.486M Shares 276,308 Est. Cost $24.40 Unrealized +17.6%

UNH UNITEDHEALTH GROUP INC 0.7%

Value $8.633M Shares 25,000 Est. Cost $298.94 Unrealized 0.0%

INCY INCYTE CORP 0.7%

Value $8.481M Shares 100,000 Est. Cost $79.04 Unrealized 0.0%

GH GUARDANT HEALTH INC 0.5%

Value $6.248M Shares 100,000 Est. Cost $26.87 Unrealized +102.5%

EXAS EXACT SCIENCES CORP 0.4%

Value $4.924M Shares 90,000 Est. Cost $74.77 Unrealized -33.2%

BBOT BRIDGEBIO ONCOLOGY THERAPEUT 0.3%

Value $3.269M Shares 282,312 Est. Cost $11.58 Unrealized —

ABSI ABSCI CORPORATION 0.2%

Value $2.959M Shares 973,260 Est. Cost $19.41 Unrealized -85.8%

CTNM CONTINEUM THERAPEUTICS INC 0.1%

Value $1.743M Shares 148,333 Est. Cost $16.10 Unrealized -49.9%

PACB PACIFIC BIOSCIENCES CALIF IN 0.1%

Value $926K Shares 723,767 Est. Cost $11.43 Unrealized -88.2%

RXRX RECURSION PHARMACEUTICALS IN 0.1%

Value $807K Shares 165,323 Est. Cost $6.72 Unrealized -21.9%

GLUE MONTE ROSA THERAPEUTICS INC 0.1%

Value $637K Shares 86,014 Est. Cost $20.37 Unrealized -74.0%

IPSC CENTURY THERAPEUTICS INC 0.1%

Value $612K Shares 1,228,190 Est. Cost $10.97 Unrealized -95.1%

TNYA TENAYA THERAPEUTICS INC 0.0%

Value $586K Shares 361,969 Est. Cost $12.86 Unrealized -92.2%

DNA GINKGO BIOWORKS HOLDINGS INC 0.0%

Value $532K Shares 36,493 Est. Cost $10.02 Unrealized +19.4%

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
WGS	GENEDX HOLDINGS CORP	3,007,164	$324M	27.0%	$9.11	+1095.5%	COM CL A	81663L200
BLFS	BIOLIFE SOLUTIONS INC	6,707,165	$171M	14.3%	$19.43	+22.1%	COM NEW	09062W204
RVMD	REVOLUTION MEDICINES INC	2,647,333	$124M	10.3%	$25.89	+51.2%	COM	76155X100
LAB	STANDARD BIOTOOLS INC	77,558,856	$101M	8.4%	$2.28	-42.6%	COM	34385P108
RNAM	AVIDITY BIOSCIENCES INC	1,780,000	$77.55M	6.5%	$14.11	+186.6%	COM	05370A108
RLAY	RELAY THERAPEUTICS INC	11,341,381	$59.2M	4.9%	$16.30	-76.6%	COM	75943R102
ILMN	ILLUMINA INC	525,000	$49.86M	4.2%	$116.47	-14.8%	COM	452327109
GPCR	STRUCTURE THERAPEUTICS INC	1,555,000	$43.54M	3.6%	$28.16	—	SPONSORED ADS	86366E106
BEAM	BEAM THERAPEUTICS INC	1,600,000	$38.83M	3.2%	$36.48	-45.5%	COM	07373V105
ALNY	ALNYLAM PHARMACEUTICALS INC	55,000	$25.08M	2.1%	$138.08	+194.9%	COM	02043Q107
TEM	TEMPUS AI INC	294,127	$23.74M	2.0%	$70.04	0.0%	CL A	88023B103
NGNE	NEUROGENE INC	1,295,361	$22.45M	1.9%	$27.94	-28.1%	COM	64135M105
MAZE	MAZE THERAPEUTICS INC	758,857	$19.68M	1.6%	$12.04	+40.2%	COM	578784100
PRME	PRIME MEDICINE INC	3,167,175	$17.55M	1.5%	$4.73	-14.1%	COM	74168J101
SPRY	ARS PHARMACEUTICALS INC	1,600,000	$16.08M	1.3%	$14.35	0.0%	COM	82835W108
HIMS	HIMS & HERS HEALTH INC	230,000	$13.05M	1.1%	$38.20	+34.1%	COM CL A	433000106
DNLI	DENALI THERAPEUTICS INC	890,000	$12.92M	1.1%	$29.48	-51.3%	COM	24823R105
SEPN	SEPTERNA INC	553,268	$10.41M	0.9%	$23.65	-44.5%	COM	81734D104
VCYT	VERACYTE INC	276,308	$9.486M	0.8%	$24.40	+17.6%	COM	92337F107
UNH	UNITEDHEALTH GROUP INC	25,000	$8.633M	0.7%	$298.94	0.0%	COM	91324P102
INCY	INCYTE CORP	100,000	$8.481M	0.7%	$79.04	0.0%	COM	45337C102
GH	GUARDANT HEALTH INC	100,000	$6.248M	0.5%	$26.87	+102.5%	COM	40131M109
EXAS	EXACT SCIENCES CORP	90,000	$4.924M	0.4%	$74.77	-33.2%	COM	30063P105
BBOT	BRIDGEBIO ONCOLOGY THERAPEUT	282,312	$3.269M	0.3%	$11.58	—	COM NEW	107924102
ABSI	ABSCI CORPORATION	973,260	$2.959M	0.2%	$19.41	-85.8%	COM	00091E109
CTNM	CONTINEUM THERAPEUTICS INC	148,333	$1.743M	0.1%	$16.10	-49.9%	CL A	21217B100
PACB	PACIFIC BIOSCIENCES CALIF IN	723,767	$926K	0.1%	$11.43	-88.2%	COM	69404D108
RXRX	RECURSION PHARMACEUTICALS IN	165,323	$807K	0.1%	$6.72	-21.9%	CL A	75629V104
GLUE	MONTE ROSA THERAPEUTICS INC	86,014	$637K	0.1%	$20.37	-74.0%	COM	61225M102
IPSC	CENTURY THERAPEUTICS INC	1,228,190	$612K	0.1%	$10.97	-95.1%	COM	15673T100
TNYA	TENAYA THERAPEUTICS INC	361,969	$586K	0.0%	$12.86	-92.2%	COM	87990A106
DNA	GINKGO BIOWORKS HOLDINGS INC	36,493	$532K	0.0%	$10.02	+19.4%	CL A NEW	37611X209