GREAT POINT PARTNERS LLC Quant / Systematic

CIK: 0001281446 · Show all filings

Period: Q2 2014 (← Previous) (Next →)

Filing Date: Aug 14, 2014

Total Value ($000): $224,814 (100.0% shares, 0.0% debt)

Holdings (38)

NBIX NEUROCRINE BIOSCIENCES INC 10.0%

Value ($000) $22,432 Shares 1,512,103 Est. Cost $15.34 Unrealized -8.0%

— HYPERION THERAPEUTICS INC 7.6%

Value ($000) $17,174 Shares 657,984 Est. Cost $26.12 Unrealized —

— DERMA SCIENCES INC 5.9%

Value ($000) $13,275 Shares 1,148,292 Est. Cost $12.46 Unrealized —

— THORATEC CORP 5.6%

Value ($000) $12,550 Shares 360,000 Est. Cost $34.86 Unrealized —

INFIQ INFINITY PHARMACEUTICALS INC 5.4%

Value ($000) $12,213 Shares 958,600 Est. Cost $12.32 Unrealized -15.4%

OM2 ORTHOFIX INTL N V 4.8%

Value ($000) $10,900 Shares 300,700 Est. Cost $31.18 Unrealized —

— OPHTHOTECH CORP 4.7%

Value ($000) $10,582 Shares 250,100 Est. Cost $42.31 Unrealized —

— PAIN THERAPEUTICS INC 4.3%

Value ($000) $9,742 Shares 1,694,256 Est. Cost $2.72 Unrealized —

— ALIMERA SCIENCES INC 4.3%

Value ($000) $9,630 Shares 1,610,316 Est. Cost $7.76 Unrealized —

— ARADIGM CORP 4.0%

Value ($000) $8,922 Shares 1,008,062 Est. Cost $8.85 Unrealized —

— OXYGEN BIOTHERAPEUTICS INC 3.8%

Value ($000) $8,631 Shares 2,115,497 Est. Cost $5.47 Unrealized —

VCYT VERACYTE INC 3.5%

Value ($000) $7,896 Shares 461,210 Est. Cost $13.47 Unrealized +6.9%

— ONCOGENEX PHARMACEUTICAL IN 3.5%

Value ($000) $7,876 Shares 2,111,590 Est. Cost $3.73 Unrealized —

— AMBIT BIOSCIENCES CORP 3.2%

Value ($000) $7,282 Shares 1,053,895 Est. Cost $12.77 Unrealized —

— ALCOBRA LTD 2.6%

Value ($000) $5,763 Shares 332,908 Est. Cost $17.94 Unrealized —

— ANTHERA PHARMACEUTICALS INC 2.3%

Value ($000) $5,085 Shares 1,500,000 Est. Cost $3.35 Unrealized —

EXAS EXACT SCIENCES CORP 1.9%

Value ($000) $4,273 Shares 250,900 Est. Cost — Unrealized —

— AVEO PHARMACEUTICALS INC 1.9%

Value ($000) $4,255 Shares 2,325,000 Est. Cost $1.83 Unrealized —

— RECRO PHARMA INC 1.9%

Value ($000) $4,171 Shares 520,776 Est. Cost $7.32 Unrealized —

— VOLCANO CORPORATION 1.8%

Value ($000) $4,097 Shares 232,645 Est. Cost $22.13 Unrealized —

— SOPHIRIS BIO INC 1.6%

Value ($000) $3,551 Shares 1,585,500 Est. Cost $4.38 Unrealized —

— KARYOPHARM THERAPEUTICS INC 1.6%

Value ($000) $3,491 Shares 75,000 Est. Cost $46.55 Unrealized —

— CARA THERAPEUTICS INC 1.5%

Value ($000) $3,408 Shares 200,219 Est. Cost $18.44 Unrealized —

— CUTERA INC 1.4%

Value ($000) $3,156 Shares 303,713 Est. Cost $10.39 Unrealized —

— ENDOLOGIX INC 1.3%

Value ($000) $2,940 Shares 193,282 Est. Cost $15.21 Unrealized —

— ONCOTHYREON INC 1.1%

Value ($000) $2,565 Shares 791,800 Est. Cost $2.99 Unrealized —

— VICAL INC 1.1%

Value ($000) $2,551 Shares 2,090,954 Est. Cost $1.22 Unrealized —

— AVANIR PHARMACEUTICALS INC 1.1%

Value ($000) $2,538 Shares 450,000 Est. Cost $5.64 Unrealized —

— SUNSHINE HEART INC 1.1%

Value ($000) $2,375 Shares 424,208 Est. Cost $11.58 Unrealized —

— OCERA THERAPEUTICS INC 1.0%

Value ($000) $2,269 Shares 296,944 Est. Cost $12.99 Unrealized —

— KALOBIOS PHARMACEUTICALS INC 0.9%

Value ($000) $2,076 Shares 910,699 Est. Cost $2.53 Unrealized —

— PSIVIDA CORP 0.7%

Value ($000) $1,645 Shares 379,060 Est. Cost $4.06 Unrealized —

— INOVIO PHARMACEUTICALS INC 0.6%

Value ($000) $1,362 Shares 126,000 Est. Cost — Unrealized —

— DIPEXIUM PHARMACEUTICALS INC 0.5%

Value ($000) $1,204 Shares 124,125 Est. Cost $10.08 Unrealized —

— MEI PHARMA INC 0.4%

Value ($000) $1,000 Shares 157,661 Est. Cost $11.25 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.3%

Value ($000) $728 Shares 151,611 Est. Cost $6.45 Unrealized —

— PROTALIX BIOTHERAPEUTICS INC 0.3%

Value ($000) $612 Shares 167,787 Est. Cost $4.15 Unrealized —

— ONCONOVA THERAPEUTICS INC 0.3%

Value ($000) $594 Shares 109,449 Est. Cost $5.43 Unrealized —

Ticker	Issuer	Shares	Value ($000)	%	Est. Cost	Unrealized	Class	CUSIP
NBIX	NEUROCRINE BIOSCIENCES INC	1,512,103	$22,432	10.0%	$15.34	-8.0%	COM	64125C109
—	HYPERION THERAPEUTICS INC	657,984	$17,174	7.6%	$26.12	—	COM	44915N101
—	DERMA SCIENCES INC	1,148,292	$13,275	5.9%	$12.46	—	COM PAR $.01	249827502
—	THORATEC CORP	360,000	$12,550	5.6%	$34.86	—	COM NEW	885175307
INFIQ	INFINITY PHARMACEUTICALS INC	958,600	$12,213	5.4%	$12.32	-15.4%	COM	45665G303
OM2	ORTHOFIX INTL N V	300,700	$10,900	4.8%	$31.18	—	COM	N6748L102
—	OPHTHOTECH CORP	250,100	$10,582	4.7%	$42.31	—	COM	683745103
—	PAIN THERAPEUTICS INC	1,694,256	$9,742	4.3%	$2.72	—	COM	69562K100
—	ALIMERA SCIENCES INC	1,610,316	$9,630	4.3%	$7.76	—	COM	016259103
—	ARADIGM CORP	1,008,062	$8,922	4.0%	$8.85	—	COM NO PAR NEW	038505400
—	OXYGEN BIOTHERAPEUTICS INC	2,115,497	$8,631	3.8%	$5.47	—	COM PAR $0.0001	69207P308
VCYT	VERACYTE INC	461,210	$7,896	3.5%	$13.47	+6.9%	COM	92337F107
—	ONCOGENEX PHARMACEUTICAL IN	2,111,590	$7,876	3.5%	$3.73	—	COM	68230A106
—	AMBIT BIOSCIENCES CORP	1,053,895	$7,282	3.2%	$12.77	—	COM	02318X100
—	ALCOBRA LTD	332,908	$5,763	2.6%	$17.94	—	SHS	M2239P109
—	ANTHERA PHARMACEUTICALS INC	1,500,000	$5,085	2.3%	$3.35	—	COM NEW	03674U201
EXAS	EXACT SCIENCES CORP	250,900	$4,273	1.9%	—	—	Put	30063P105
—	AVEO PHARMACEUTICALS INC	2,325,000	$4,255	1.9%	$1.83	—	COM	053588109
—	RECRO PHARMA INC	520,776	$4,171	1.9%	$7.32	—	COM	75629F109
—	VOLCANO CORPORATION	232,645	$4,097	1.8%	$22.13	—	COM	928645100
—	SOPHIRIS BIO INC	1,585,500	$3,551	1.6%	$4.38	—	COM NEW	83578Q209
—	KARYOPHARM THERAPEUTICS INC	75,000	$3,491	1.6%	$46.55	—	COM	48576U106
—	CARA THERAPEUTICS INC	200,219	$3,408	1.5%	$18.44	—	COM	140755109
—	CUTERA INC	303,713	$3,156	1.4%	$10.39	—	COM	232109108
—	ENDOLOGIX INC	193,282	$2,940	1.3%	$15.21	—	COM	29266S106
—	ONCOTHYREON INC	791,800	$2,565	1.1%	$2.99	—	COM	682324108
—	VICAL INC	2,090,954	$2,551	1.1%	$1.22	—	COM	925602104
—	AVANIR PHARMACEUTICALS INC	450,000	$2,538	1.1%	$5.64	—	CL A NEW	05348P401
—	SUNSHINE HEART INC	424,208	$2,375	1.1%	$11.58	—	COM	86782U106
—	OCERA THERAPEUTICS INC	296,944	$2,269	1.0%	$12.99	—	COM	67552A108
—	KALOBIOS PHARMACEUTICALS INC	910,699	$2,076	0.9%	$2.53	—	COM	48344T100
—	PSIVIDA CORP	379,060	$1,645	0.7%	$4.06	—	COM	74440J101
—	INOVIO PHARMACEUTICALS INC	126,000	$1,362	0.6%	—	—	Put	45773H201
—	DIPEXIUM PHARMACEUTICALS INC	124,125	$1,204	0.5%	$10.08	—	COM	25456J104
—	MEI PHARMA INC	157,661	$1,000	0.4%	$11.25	—	COM NEW	55279B202
—	STREAMLINE HEALTH SOLUTIONS	151,611	$728	0.3%	$6.45	—	COM	86323X106
—	PROTALIX BIOTHERAPEUTICS INC	167,787	$612	0.3%	$4.15	—	COM	74365A101
—	ONCONOVA THERAPEUTICS INC	109,449	$594	0.3%	$5.43	—	COM	68232V108