GREAT POINT PARTNERS LLC Quant / Systematic

Location: Greenwich, CT

CIK: 0001281446 · Show all filings

Period: Q3 2014 (← Previous) (Next →)

Filing Date: Nov 14, 2014

Total Value: $233M (100.0% shares, 0.0% debt)

Holdings (37)

— HYPERION THERAPEUTICS INC 8.6%

Value $20.02M Shares 793,864 Est. Cost $25.97 Unrealized —

NBIX NEUROCRINE BIOSCIENCES INC 7.8%

Value $18.2M Shares 1,161,739 Est. Cost $15.34 Unrealized -2.6%

INFIQ INFINITY PHARMACEUTICALS INC 6.3%

Value $14.76M Shares 1,100,000 Est. Cost $12.26 Unrealized -2.9%

— ALIMERA SCIENCES INC 6.1%

Value $14.2M Shares 2,619,853 Est. Cost $6.86 Unrealized —

— OPHTHOTECH CORP 5.0%

Value $11.68M Shares 300,000 Est. Cost $41.75 Unrealized —

— ENDOLOGIX INC 4.4%

Value $10.32M Shares 973,200 Est. Cost $11.52 Unrealized —

— DERMA SCIENCES INC 4.2%

Value $9.676M Shares 1,161,604 Est. Cost $12.41 Unrealized —

— ARADIGM CORP CMN 4.2%

Value $9.667M Shares 1,008,062 Est. Cost $8.85 Unrealized —

— AMBIT BIOSCIENCES CORP 4.0%

Value $9.24M Shares 600,000 Est. Cost $12.77 Unrealized —

— OCERA THERAPEUTICS INC 3.9%

Value $9.111M Shares 1,859,315 Est. Cost $6.19 Unrealized —

OM2 ORTHOFIX INTL N V 3.5%

Value $8.2M Shares 264,873 Est. Cost $31.18 Unrealized —

AUPH AURINIA PHARMACEUTICALS INC 3.4%

Value $7.917M Shares 2,474,076 Est. Cost $3.55 Unrealized 0.0%

EXEL EXELIXIS INC 3.4%

Value $7.803M Shares 5,100,000 Est. Cost $3.21 Unrealized 0.0%

— ALCOBRA LTD 3.2%

Value $7.522M Shares 487,200 Est. Cost $17.94 Unrealized —

— ONCOTHYREON INC 3.2%

Value $7.503M Shares 3,907,952 Est. Cost $2.14 Unrealized —

— PAIN THERAPEUTICS INC 3.1%

Value $7.108M Shares 1,817,889 Est. Cost $2.80 Unrealized —

— AASTROM BIOSCIENCES INC 2.7%

Value $6.185M Shares 2,170,000 Est. Cost $2.85 Unrealized —

EBS EMERGENT BIOSOLUTIONS INC 2.7%

Value $6.18M Shares 290,000 Est. Cost $22.90 Unrealized 0.0%

VCYT VERACYTE INC 2.5%

Value $5.921M Shares 607,296 Est. Cost $13.38 Unrealized -1.9%

— HEARTWARE INTL INC 2.3%

Value $5.434M Shares 70,000 Est. Cost $77.63 Unrealized —

— ONCOGENEX PHARMACEUTICALS IN 2.1%

Value $4.79M Shares 1,793,942 Est. Cost $3.73 Unrealized —

— SOPHIRIS BIO INC 2.0%

Value $4.646M Shares 1,585,500 Est. Cost $4.38 Unrealized —

— TENAX THERAPEUTICS INC 1.9%

Value $4.384M Shares 1,115,497 Est. Cost $3.93 Unrealized —

— VICAL INC 1.5%

Value $3.388M Shares 3,025,000 Est. Cost $1.19 Unrealized —

— CUTERA INC 1.4%

Value $3.182M Shares 315,000 Est. Cost $10.38 Unrealized —

— SUNESIS PHARMACEUTICALS INC 1.2%

Value $2.856M Shares 400,000 Est. Cost — Unrealized —

— ANTHERA PHARMACEUTICALS INC 1.2%

Value $2.748M Shares 1,431,196 Est. Cost $3.35 Unrealized —

— CHEMOCENTRYX INC 0.9%

Value $2.177M Shares 483,741 Est. Cost $4.50 Unrealized —

— WAFERGEN BIO-SYSTEMS INC 0.8%

Value $1.834M Shares 421,509 Est. Cost $4.35 Unrealized —

— ONCONOVA THERAPEUTICS INC 0.6%

Value $1.487M Shares 345,824 Est. Cost $4.66 Unrealized —

— MEI PHARMA INC 0.5%

Value $1.088M Shares 157,661 Est. Cost $11.25 Unrealized —

— AMARIN CORP PLC 0.4%

Value $1.007M Shares 923,534 Est. Cost $1.09 Unrealized —

— STREAMLINE HEALTH SOLUTIONS 0.3%

Value $702K Shares 151,611 Est. Cost $6.45 Unrealized —

— THORATEC CORP 0.3%

Value $596K Shares 22,300 Est. Cost $34.86 Unrealized —

— ALCOBRA LTD 0.2%

Value $559K Shares 36,200 Est. Cost $17.94 Unrealized —

— CARA THERAPEUTICS INC 0.2%

Value $397K Shares 47,321 Est. Cost $18.44 Unrealized —

— ZAFGEN INC 0.1%

Value $331K Shares 16,855 Est. Cost $19.64 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
—	HYPERION THERAPEUTICS INC	793,864	$20.02M	8.6%	$25.97	—	COM	44915N101
NBIX	NEUROCRINE BIOSCIENCES INC	1,161,739	$18.2M	7.8%	$15.34	-2.6%	COM	64125C109
INFIQ	INFINITY PHARMACEUTICALS INC	1,100,000	$14.76M	6.3%	$12.26	-2.9%	COM	45665G303
—	ALIMERA SCIENCES INC	2,619,853	$14.2M	6.1%	$6.86	—	COM	016259103
—	OPHTHOTECH CORP	300,000	$11.68M	5.0%	$41.75	—	COM	683745103
—	ENDOLOGIX INC	973,200	$10.32M	4.4%	$11.52	—	COM	29266S106
—	DERMA SCIENCES INC	1,161,604	$9.676M	4.2%	$12.41	—	COM PAR $.01	249827502
—	ARADIGM CORP CMN	1,008,062	$9.667M	4.2%	$8.85	—	COM	038505400
—	AMBIT BIOSCIENCES CORP	600,000	$9.24M	4.0%	$12.77	—	COM	02318X100
—	OCERA THERAPEUTICS INC	1,859,315	$9.111M	3.9%	$6.19	—	COM	67552A108
OM2	ORTHOFIX INTL N V	264,873	$8.2M	3.5%	$31.18	—	COM	N6748L102
AUPH	AURINIA PHARMACEUTICALS INC	2,474,076	$7.917M	3.4%	$3.55	0.0%	COM	05156V102
EXEL	EXELIXIS INC	5,100,000	$7.803M	3.4%	$3.21	0.0%	COM	30161Q104
—	ALCOBRA LTD	487,200	$7.522M	3.2%	$17.94	—	Call	M2239P109
—	ONCOTHYREON INC	3,907,952	$7.503M	3.2%	$2.14	—	COM	682324108
—	PAIN THERAPEUTICS INC	1,817,889	$7.108M	3.1%	$2.80	—	COM	69562K100
—	AASTROM BIOSCIENCES INC	2,170,000	$6.185M	2.7%	$2.85	—	COM PAR$	00253U404
EBS	EMERGENT BIOSOLUTIONS INC	290,000	$6.18M	2.7%	$22.90	0.0%	COM	29089Q105
VCYT	VERACYTE INC	607,296	$5.921M	2.5%	$13.38	-1.9%	COM	92337F107
—	HEARTWARE INTL INC	70,000	$5.434M	2.3%	$77.63	—	COM	422368100
—	ONCOGENEX PHARMACEUTICALS IN	1,793,942	$4.79M	2.1%	$3.73	—	COM	68230A106
—	SOPHIRIS BIO INC	1,585,500	$4.646M	2.0%	$4.38	—	COM NEW	83578Q209
—	TENAX THERAPEUTICS INC	1,115,497	$4.384M	1.9%	$3.93	—	COM	88032L100
—	VICAL INC	3,025,000	$3.388M	1.5%	$1.19	—	COM	925602104
—	CUTERA INC	315,000	$3.182M	1.4%	$10.38	—	COM	232109108
—	SUNESIS PHARMACEUTICALS INC	400,000	$2.856M	1.2%	—	—	Call	867328601
—	ANTHERA PHARMACEUTICALS INC	1,431,196	$2.748M	1.2%	$3.35	—	COM NEW	03674U201
—	CHEMOCENTRYX INC	483,741	$2.177M	0.9%	$4.50	—	COM	16383L106
—	WAFERGEN BIO-SYSTEMS INC	421,509	$1.834M	0.8%	$4.35	—	COM PAR$	93041P308
—	ONCONOVA THERAPEUTICS INC	345,824	$1.487M	0.6%	$4.66	—	COM	68232V108
—	MEI PHARMA INC	157,661	$1.088M	0.5%	$11.25	—	COM NEW	55279B202
—	AMARIN CORP PLC	923,534	$1.007M	0.4%	$1.09	—	SPONS ADR NEW	023111206
—	STREAMLINE HEALTH SOLUTIONS	151,611	$702K	0.3%	$6.45	—	COM	86323X106
—	THORATEC CORP	22,300	$596K	0.3%	$34.86	—	COM NEW	885175307
—	ALCOBRA LTD	36,200	$559K	0.2%	$17.94	—	Put	M2239P109
—	CARA THERAPEUTICS INC	47,321	$397K	0.2%	$18.44	—	COM	140755109
—	ZAFGEN INC	16,855	$331K	0.1%	$19.64	—	COM	98885E103