ACUTA CAPITAL PARTNERS, LLC Hedge Fund

Location: Redwood City, CA

CIK: 0001582844 · Show all filings

Period: Q2 2022 (← Previous) (Next →)

Filing Date: Aug 15, 2022

Total Value: $179M (100.0% shares, 0.0% debt)

Holdings (43)

APLS APELLIS PHARMACEUTICALS INC 14.0%

Value $25.05M Shares 554,000 Est. Cost $38.98 Unrealized +17.0%

WHWK AADI BIOSCIENCES INC 10.5%

Value $18.84M Shares 1,529,402 Est. Cost $30.48 Unrealized -51.3%

— VISTAGEN THERAPEUTICS INC 5.6%

Value $9.998M Shares 11,361,451 Est. Cost $2.01 Unrealized —

KURA KURA ONCOLOGY INC. COMMON STOCK 5.5%

Value $9.834M Shares 536,500 Est. Cost $15.03 Unrealized -4.3%

— BCLS ACQUISITION CORP- CL A 4.7%

Value $8.347M Shares 843,122 Est. Cost $11.14 Unrealized —

XENE XENON PHARMACEUTICALS INC 4.6%

Value $8.289M Shares 272,500 Est. Cost $17.89 Unrealized +69.1%

— BELLUS HEALTH INC 4.2%

Value $7.54M Shares 816,000 Est. Cost $6.40 Unrealized —

CLDX CELLDEX THERAPEUTICS INC 4.0%

Value $7.204M Shares 267,195 Est. Cost $7.56 Unrealized +284.2%

RLMD RELMADA THERAPEUTICS INC 3.7%

Value $6.694M Shares 352,500 Est. Cost $22.22 Unrealized -1.9%

— MIRATI THERAPEUTICS 3.5%

Value $6.344M Shares 94,500 Est. Cost $89.16 Unrealized —

— JIYA ACQUISITION CORP -CL A 3.1%

Value $5.552M Shares 562,500 Est. Cost $10.30 Unrealized —

— IVERIC BIO INC 3.0%

Value $5.422M Shares 563,607 Est. Cost $7.63 Unrealized —

— ROCHE GS 3.0%

Value $5.338M Shares 16,000 Est. Cost $333.63 Unrealized —

RCUS ARCUS BIOSCIENCES INC 2.4%

Value $4.244M Shares 167,500 Est. Cost $24.49 Unrealized 0.0%

SNDX SYNDAX PHARMACEUTICALS INC 2.2%

Value $3.944M Shares 205,003 Est. Cost $17.89 Unrealized -6.9%

— HEALTH SCIENCES ACQUISITIONS 2.2%

Value $3.909M Shares 392,500 Est. Cost $11.00 Unrealized —

— MERUS BV 1.9%

Value $3.487M Shares 154,000 Est. Cost $26.72 Unrealized —

— PRECISION BIOSCIENCES INC 1.8%

Value $3.281M Shares 2,050,359 Est. Cost $1.60 Unrealized —

UTHR UNITED THERAPEUTICS CORP DEL 1.7%

Value $3.063M Shares 13,000 Est. Cost $203.30 Unrealized 0.0%

— HORIZON THERAPEUTICS PLC 1.6%

Value $2.862M Shares 35,888 Est. Cost $103.30 Unrealized —

MIST MILESTONE PHARMACEUTICALS IN 1.6%

Value $2.812M Shares 457,200 Est. Cost $6.23 Unrealized -1.4%

VRDN VIRIDIAN THERAPEUTICS INC 1.5%

Value $2.708M Shares 234,026 Est. Cost $17.08 Unrealized -21.3%

ACRS ACLARIS THERAPEU 1.5%

Value $2.692M Shares 192,835 Est. Cost $16.31 Unrealized -14.1%

GHRS GH RESEARCH PLC 1.4%

Value $2.428M Shares 243,250 Est. Cost $20.48 Unrealized -36.5%

EYPT EYEPOINT PHARMACEUTICALS INC 1.3%

Value $2.388M Shares 303,396 Est. Cost $11.19 Unrealized -10.2%

ARWR ARROWHEAD PHARMACEUTICALS INC 1.2%

Value $2.18M Shares 61,926 Est. Cost $43.08 Unrealized -12.7%

PMVP PMV PHARMACEUTICALS INC 1.2%

Value $2.173M Shares 152,500 Est. Cost $17.30 Unrealized -15.9%

RZLT REZOLUTE INC 1.2%

Value $2.084M Shares 645,136 Est. Cost $3.32 Unrealized 0.0%

IOVA IOVANCE BIOTHERAPEUTICS INC 0.9%

Value $1.704M Shares 154,356 Est. Cost $19.89 Unrealized -34.1%

PYXS PYXIS ONCOLOGY INC 0.9%

Value $1.535M Shares 645,149 Est. Cost $5.39 Unrealized -50.6%

VTYX VENTYX BIOSCIENCES INC 0.8%

Value $1.492M Shares 122,000 Est. Cost $14.02 Unrealized +6.6%

ENTA ENANTA PHARMACEUTICALS INC 0.7%

Value $1.3M Shares 27,500 Est. Cost $55.17 Unrealized -1.6%

— ITEOS THERAPEUTICS INC 0.7%

Value $1.277M Shares 62,000 Est. Cost $20.60 Unrealized —

ACAD ACADIA PHARMACEUTICALS INC 0.6%

Value $1.007M Shares 71,500 Est. Cost $18.68 Unrealized 0.0%

FULC FULCRUM THERAPEUTICS INC 0.5%

Value $980K Shares 200,000 Est. Cost $11.72 Unrealized -16.6%

— AC IMMUNE SA 0.2%

Value $354K Shares 100,000 Est. Cost — Unrealized —

— ATHIRA PHARMA INC 0.2%

Value $340K Shares 100,000 Est. Cost — Unrealized —

GOSS GOSSAMER BIO INC 0.1%

Value $268K Shares 32,000 Est. Cost $7.75 Unrealized 0.0%

— VERASTEM INC 0.1%

Value $232K Shares 200,000 Est. Cost $2.55 Unrealized —

— SPRINGWORKS THERAPEUTICS INC 0.1%

Value $123K Shares 5,000 Est. Cost $24.60 Unrealized —

TRVI TREVI THERAPEUTICS INC 0.1%

Value $98,000 Shares 35,000 Est. Cost $2.46 Unrealized 0.0%

OCUL OCULAR THERAPEUTIX INC 0.0%

Value $53,000 Shares 13,171 Est. Cost $3.78 Unrealized 0.0%

— NUVATION BIO INC 0.0%

Value $25,000 Shares 90,832 Est. Cost $0.28 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
APLS	APELLIS PHARMACEUTICALS INC	554,000	$25.05M	14.0%	$38.98	+17.0%	COM	03753U106
WHWK	AADI BIOSCIENCES INC	1,529,402	$18.84M	10.5%	$30.48	-51.3%	COM	00032Q104
—	VISTAGEN THERAPEUTICS INC	11,361,451	$9.998M	5.6%	$2.01	—	COM NEW	92840H202
KURA	KURA ONCOLOGY INC. COMMON STOCK	536,500	$9.834M	5.5%	$15.03	-4.3%	COM	50127T109
—	BCLS ACQUISITION CORP- CL A	843,122	$8.347M	4.7%	$11.14	—	COM CL A	G0904B105
XENE	XENON PHARMACEUTICALS INC	272,500	$8.289M	4.6%	$17.89	+69.1%	COM	98420N105
—	BELLUS HEALTH INC	816,000	$7.54M	4.2%	$6.40	—	COM NEW	07987C204
CLDX	CELLDEX THERAPEUTICS INC	267,195	$7.204M	4.0%	$7.56	+284.2%	COM NEW	15117B202
RLMD	RELMADA THERAPEUTICS INC	352,500	$6.694M	3.7%	$22.22	-1.9%	COM	75955J402
—	MIRATI THERAPEUTICS	94,500	$6.344M	3.5%	$89.16	—	COM	60468T105
—	JIYA ACQUISITION CORP -CL A	562,500	$5.552M	3.1%	$10.30	—	COM CL A	47760M102
—	IVERIC BIO INC	563,607	$5.422M	3.0%	$7.63	—	COM	46583P102
—	ROCHE GS	16,000	$5.338M	3.0%	$333.63	—	COM	993960LE1
RCUS	ARCUS BIOSCIENCES INC	167,500	$4.244M	2.4%	$24.49	0.0%	COM	03969F109
SNDX	SYNDAX PHARMACEUTICALS INC	205,003	$3.944M	2.2%	$17.89	-6.9%	COM	87164F105
—	HEALTH SCIENCES ACQUISITIONS	392,500	$3.909M	2.2%	$11.00	—	ORD SHS	G4411D109
—	MERUS BV	154,000	$3.487M	1.9%	$26.72	—	COM	N5749R100
—	PRECISION BIOSCIENCES INC	2,050,359	$3.281M	1.8%	$1.60	—	COM	74019P108
UTHR	UNITED THERAPEUTICS CORP DEL	13,000	$3.063M	1.7%	$203.30	0.0%	COM	91307C102
—	HORIZON THERAPEUTICS PLC	35,888	$2.862M	1.6%	$103.30	—	SHS	G46188101
MIST	MILESTONE PHARMACEUTICALS IN	457,200	$2.812M	1.6%	$6.23	-1.4%	COM	59935V107
VRDN	VIRIDIAN THERAPEUTICS INC	234,026	$2.708M	1.5%	$17.08	-21.3%	COM	92790C104
ACRS	ACLARIS THERAPEU	192,835	$2.692M	1.5%	$16.31	-14.1%	COM	00461U105
GHRS	GH RESEARCH PLC	243,250	$2.428M	1.4%	$20.48	-36.5%	ORDINARY SHARES	G3855L106
EYPT	EYEPOINT PHARMACEUTICALS INC	303,396	$2.388M	1.3%	$11.19	-10.2%	COM NEW	30233G209
ARWR	ARROWHEAD PHARMACEUTICALS INC	61,926	$2.18M	1.2%	$43.08	-12.7%	COM	04280A100
PMVP	PMV PHARMACEUTICALS INC	152,500	$2.173M	1.2%	$17.30	-15.9%	COM	69353Y103
RZLT	REZOLUTE INC	645,136	$2.084M	1.2%	$3.32	0.0%	COM NEW	76200L309
IOVA	IOVANCE BIOTHERAPEUTICS INC	154,356	$1.704M	0.9%	$19.89	-34.1%	COM	462260100
PYXS	PYXIS ONCOLOGY INC	645,149	$1.535M	0.9%	$5.39	-50.6%	COMMON STOCK	747324101
VTYX	VENTYX BIOSCIENCES INC	122,000	$1.492M	0.8%	$14.02	+6.6%	COM	92332V107
ENTA	ENANTA PHARMACEUTICALS INC	27,500	$1.3M	0.7%	$55.17	-1.6%	COM	29251M106
—	ITEOS THERAPEUTICS INC	62,000	$1.277M	0.7%	$20.60	—	COM	46565G104
ACAD	ACADIA PHARMACEUTICALS INC	71,500	$1.007M	0.6%	$18.68	0.0%	COM	004225108
FULC	FULCRUM THERAPEUTICS INC	200,000	$980K	0.5%	$11.72	-16.6%	COM	359616109
—	AC IMMUNE SA	100,000	$354K	0.2%	—	—	Call	99P1VHX22
—	ATHIRA PHARMA INC	100,000	$340K	0.2%	—	—	Call	99P19TV23
GOSS	GOSSAMER BIO INC	32,000	$268K	0.1%	$7.75	0.0%	COM	38341P102
—	VERASTEM INC	200,000	$232K	0.1%	$2.55	—	COM	92337C104
—	SPRINGWORKS THERAPEUTICS INC	5,000	$123K	0.1%	$24.60	—	COM	85205L107
TRVI	TREVI THERAPEUTICS INC	35,000	$98,000	0.1%	$2.46	0.0%	COM	89532M101
OCUL	OCULAR THERAPEUTIX INC	13,171	$53,000	0.0%	$3.78	0.0%	COM	67576A100
—	NUVATION BIO INC	90,832	$25,000	0.0%	$0.28	—	*W EXP 07/07/202	67080N119