Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q4 2022 (← Previous) (Next →)
Filing Date: Feb 14, 2023
Total Value: $1.685B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Share Price | Est. Cost/Share | Unrealized @ Report Date | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|---|
| — | Karuna Therapeutics Inc | 2,073,124 | $407M | 24.2% | $196.50 | $32.21 | — | COM | 48576A100 |
| NTRA | Natera Inc | 3,100,560 | $125M | 7.4% | $40.17 * | $9.81 | +320.0% | COM | 632307104 |
| — | Aerovate Therapeutics Inc | 3,758,686 | $110M | 6.5% | $29.30 | $22.83 | — | COM | 008064107 |
| ASND | Ascendis Pharma A/S | 880,800 | $108M | 6.4% | $122.13 | $92.54 | — | SPONSORED ADR | 04351P101 |
| SNY | Sanofi SA | 1,965,475 | $95.19M | 5.6% | $48.43 | $43.46 | — | SPONSORED ADR | 80105N105 |
| — | Cincor Pharma Inc | 6,073,949 | $74.65M | 4.4% | $12.29 | $18.81 | — | COM | 17240Y109 |
| MRK | Merck & Co Inc | 603,356 | $66.94M | 4.0% | $110.95 * | $80.10 | +15.9% | COM | 58933Y105 |
| VERA | Vera Therapeutics Inc | 3,181,442 | $61.56M | 3.7% | $19.35 * | $16.04 | +12.9% | CL A | 92337R101 |
| — | Horizon Therapeutics PLC | 413,173 | $47.02M | 2.8% | $113.80 | $113.80 | — | SHS | G46188101 |
| VRTX | Vertex Pharmaceuticals Inc | 156,989 | $45.34M | 2.7% | $288.78 * | $304.77 | 0.0% | COM | 92532F100 |
| AZN | AstraZeneca PLC | 613,673 | $41.61M | 2.5% | $67.80 | $60.02 | — | SPONSORED ADR | 046353108 |
| BMRN | Biomarin Pharmaceutical Inc | 394,643 | $40.84M | 2.4% | $103.49 * | $84.75 | +10.8% | COM | 09061G101 |
| — | Reata Pharmaceuticals Inc | 992,029 | $37.69M | 2.2% | $37.99 | $32.98 | — | CL A | 75615P103 |
| SRPT | Sarepta Therapeutics Inc | 247,955 | $32.13M | 1.9% | $129.58 * | $93.67 | +23.7% | COM | 803607100 |
| — | CTI Biopharma Corp | 4,606,527 | $27.69M | 1.6% | $6.01 | $5.40 | — | COM | 12648L601 |
| — | Inhibrx Inc | 1,110,183 | $27.35M | 1.6% | $24.64 | $24.55 | — | COM | 45720L107 |
| UTHR | United Therapeutics Corp | 89,207 | $24.81M | 1.5% | $278.09 * | $155.83 | +62.0% | COM | 91307C102 |
| ALNY | Alnylam Pharmaceuticals Inc | 100,000 | $23.77M | 1.4% | $237.65 * | $213.29 | 0.0% | Call | 02043Q107 |
| CYTK | Cytokinetics Inc | 508,930 | $23.32M | 1.4% | $45.82 * | $39.04 | +10.0% | COM | 23282W605 |
| — | Chinook Therapeutics Inc | 806,459 | $21.13M | 1.3% | $26.20 | $23.12 | — | COM | 16961L106 |
| ZNTL | Zentalis Pharmaceuticals Inc | 1,004,045 | $20.22M | 1.2% | $20.14 * | $24.62 | -12.6% | COM | 98943L107 |
| — | Prometheus Biosciences Inc | 176,545 | $19.42M | 1.2% | $110.00 | $45.26 | — | COM | 74349U108 |
| SNDX | Syndax Pharmaceuticals Inc | 703,074 | $17.89M | 1.1% | $25.45 * | $19.87 | +17.4% | COM | 87164F105 |
| ALGN | Align Technology Inc | 83,100 | $17.53M | 1.0% | $210.90 * | $200.17 | 0.0% | COM | 016255101 |
| IMTX | Immatics NV | 2,000,776 | $17.43M | 1.0% | $8.71 * | $10.58 | -2.2% | SHS | N44445109 |
| DXCM | Dexcom Inc | 140,678 | $15.93M | 0.9% | $113.24 * | $92.37 | +18.9% | COM | 252131107 |
| — | Iveric Bio Inc | 638,398 | $13.67M | 0.8% | $21.41 | $16.85 | — | COM | 46583P102 |
| ALNY | Alnylam Pharmaceuticals Inc | 56,448 | $13.41M | 0.8% | $237.65 * | $213.29 | 0.0% | COM | 02043Q107 |
| TVTX | Travere Therapeutics Inc | 578,268 | $12.16M | 0.7% | $21.03 | $23.70 | -10.6% | COM | 89422G107 |
| — | Y-mAbs Therapeutics Inc | 2,194,278 | $10.71M | 0.6% | $4.88 | $26.75 | — | COM | 984241109 |
| IDYA | IDEAYA Biosciences Inc | 474,530 | $8.622M | 0.5% | $18.17 * | $12.99 | +29.5% | COM | 45166A102 |
| — | ImmunoGen Inc | 1,686,154 | $8.363M | 0.5% | $4.96 | $5.69 | — | COM | 45253H101 |
| KURA | Kura Oncology Inc | 593,561 | $7.366M | 0.4% | $12.41 * | $14.54 | 0.0% | COM | 50127T109 |
| — | Agenus Inc | 2,894,057 | $6.946M | 0.4% | $2.40 | $2.07 | — | COM | 00847G705 |
| RCUS | Arcus Biosciences Inc | 314,811 | $6.51M | 0.4% | $20.68 * | $26.45 | +4.1% | COM | 03969F109 |
| GERN | Geron Corp | 2,369,100 | $5.733M | 0.3% | $2.42 * | $1.40 | +60.0% | Call | 374163103 |
| FULC | Fulcrum Therapeutics Inc | 631,411 | $4.597M | 0.3% | $7.28 * | $7.16 | -8.9% | COM | 359616109 |
| GRTX | Galera Therapeutics Inc | 3,083,712 | $4.595M | 0.3% | $1.49 * | $12.19 | -86.7% | COM | 36338D108 |
| CYTK | Cytokinetics Inc | 100,000 | $4.582M | 0.3% | $45.82 * | $39.04 | +10.0% | Call | 23282W605 |
| — | Inozyme Pharma Inc | 3,655,308 | $3.838M | 0.2% | $1.05 | $16.71 | — | COM | 45790W108 |
| — | Nextcure Inc | 2,671,856 | $3.767M | 0.2% | $1.41 | $10.01 | — | COM | 65343E108 |
| — | Nucana PLC | 5,599,999 | $3.696M | 0.2% | $0.66 | $9.47 | — | SPONSORED ADR | 67022C106 |
| — | Bolt Biotherapeutics Inc | 2,754,437 | $3.581M | 0.2% | $1.30 | $32.91 | — | COM | 097702104 |
| GERN | Geron Corp | 1,459,589 | $3.532M | 0.2% | $2.42 * | $1.40 | +60.0% | COM | 374163103 |
| — | Agenus Inc | 1,267,000 | $3.041M | 0.2% | $2.40 | $2.07 | — | Call | 00847G705 |
| — | CTI Biopharma Corp | 410,000 | $2.464M | 0.1% | $6.01 | $5.40 | — | Call | 12648L601 |
| PDSB | PDS Biotechnology Corp | 142,635 | $1.883M | 0.1% | $13.20 * | $8.36 | -15.6% | COM | 70465T107 |
| — | Nucana PLC | 2,400,000 | $1.584M | 0.1% | $0.66 | $4.99 | — | COMMON SHARES | GB00BYWYV |
| — | ObsEva SA | 4,749,623 | $689K | 0.0% | $0.14 | $13.49 | — | COM | H5861P103 |
| — | Synlogic Inc | 574,972 | $437K | 0.0% | $0.76 | $9.38 | — | COM | 87166L100 |
| — | Fusion Pharmaceuticals Inc | 117,099 | $369K | 0.0% | $3.15 | $6.28 | — | COM | 36118A100 |