Sofinnova Investments, Inc. Quant / Systematic

Location: Menlo Park, CA

CIK: 0001631134 · Show all filings

Period: Q4 2022 (← Previous) (Next →)

Filing Date: Feb 14, 2023

Total Value: $1.685B (100.0% shares, 0.0% debt)

Holdings (51)

Karuna Therapeutics Inc 24.2%
Value $407M Shares 2,073,124 Est. Cost $32.21 Unrealized
NTRA Natera Inc 7.4%
Value $125M Shares 3,100,560 Est. Cost $9.81 Unrealized +320.0%
Aerovate Therapeutics Inc 6.5%
Value $110M Shares 3,758,686 Est. Cost $22.83 Unrealized
ASND Ascendis Pharma A/S 6.4%
Value $108M Shares 880,800 Est. Cost $92.54 Unrealized
SNY Sanofi SA 5.6%
Value $95.19M Shares 1,965,475 Est. Cost $43.46 Unrealized
Cincor Pharma Inc 4.4%
Value $74.65M Shares 6,073,949 Est. Cost $18.81 Unrealized
MRK Merck & Co Inc 4.0%
Value $66.94M Shares 603,356 Est. Cost $80.10 Unrealized +15.9%
VERA Vera Therapeutics Inc 3.7%
Value $61.56M Shares 3,181,442 Est. Cost $16.04 Unrealized +12.9%
Horizon Therapeutics PLC 2.8%
Value $47.02M Shares 413,173 Est. Cost $113.80 Unrealized
VRTX Vertex Pharmaceuticals Inc 2.7%
Value $45.34M Shares 156,989 Est. Cost $304.77 Unrealized 0.0%
AZN AstraZeneca PLC 2.5%
Value $41.61M Shares 613,673 Est. Cost $60.02 Unrealized
BMRN Biomarin Pharmaceutical Inc 2.4%
Value $40.84M Shares 394,643 Est. Cost $84.75 Unrealized +10.8%
Reata Pharmaceuticals Inc 2.2%
Value $37.69M Shares 992,029 Est. Cost $32.98 Unrealized
SRPT Sarepta Therapeutics Inc 1.9%
Value $32.13M Shares 247,955 Est. Cost $93.67 Unrealized +23.7%
CTI Biopharma Corp 1.6%
Value $27.69M Shares 4,606,527 Est. Cost $5.40 Unrealized
Inhibrx Inc 1.6%
Value $27.35M Shares 1,110,183 Est. Cost $24.55 Unrealized
UTHR United Therapeutics Corp 1.5%
Value $24.81M Shares 89,207 Est. Cost $155.83 Unrealized +62.0%
ALNY Alnylam Pharmaceuticals Inc 1.4%
Value $23.77M Shares 100,000 Est. Cost $213.29 Unrealized 0.0%
CYTK Cytokinetics Inc 1.4%
Value $23.32M Shares 508,930 Est. Cost $39.04 Unrealized +10.0%
Chinook Therapeutics Inc 1.3%
Value $21.13M Shares 806,459 Est. Cost $23.12 Unrealized
ZNTL Zentalis Pharmaceuticals Inc 1.2%
Value $20.22M Shares 1,004,045 Est. Cost $24.62 Unrealized -12.6%
Prometheus Biosciences Inc 1.2%
Value $19.42M Shares 176,545 Est. Cost $45.26 Unrealized
SNDX Syndax Pharmaceuticals Inc 1.1%
Value $17.89M Shares 703,074 Est. Cost $19.87 Unrealized +17.4%
ALGN Align Technology Inc 1.0%
Value $17.53M Shares 83,100 Est. Cost $200.17 Unrealized 0.0%
IMTX Immatics NV 1.0%
Value $17.43M Shares 2,000,776 Est. Cost $10.58 Unrealized -2.2%
DXCM Dexcom Inc 0.9%
Value $15.93M Shares 140,678 Est. Cost $92.37 Unrealized +18.9%
Iveric Bio Inc 0.8%
Value $13.67M Shares 638,398 Est. Cost $16.85 Unrealized
ALNY Alnylam Pharmaceuticals Inc 0.8%
Value $13.41M Shares 56,448 Est. Cost $213.29 Unrealized 0.0%
TVTX Travere Therapeutics Inc 0.7%
Value $12.16M Shares 578,268 Est. Cost $23.70 Unrealized -10.6%
Y-mAbs Therapeutics Inc 0.6%
Value $10.71M Shares 2,194,278 Est. Cost $26.75 Unrealized
IDYA IDEAYA Biosciences Inc 0.5%
Value $8.622M Shares 474,530 Est. Cost $12.99 Unrealized +29.5%
ImmunoGen Inc 0.5%
Value $8.363M Shares 1,686,154 Est. Cost $5.69 Unrealized
KURA Kura Oncology Inc 0.4%
Value $7.366M Shares 593,561 Est. Cost $14.54 Unrealized 0.0%
Agenus Inc 0.4%
Value $6.946M Shares 2,894,057 Est. Cost $2.07 Unrealized
RCUS Arcus Biosciences Inc 0.4%
Value $6.51M Shares 314,811 Est. Cost $26.45 Unrealized +4.1%
GERN Geron Corp 0.3%
Value $5.733M Shares 2,369,100 Est. Cost $1.40 Unrealized +60.0%
FULC Fulcrum Therapeutics Inc 0.3%
Value $4.597M Shares 631,411 Est. Cost $7.16 Unrealized -8.9%
GRTX Galera Therapeutics Inc 0.3%
Value $4.595M Shares 3,083,712 Est. Cost $12.19 Unrealized -86.7%
CYTK Cytokinetics Inc 0.3%
Value $4.582M Shares 100,000 Est. Cost $39.04 Unrealized +10.0%
Inozyme Pharma Inc 0.2%
Value $3.838M Shares 3,655,308 Est. Cost $16.71 Unrealized
Nextcure Inc 0.2%
Value $3.767M Shares 2,671,856 Est. Cost $10.01 Unrealized
Nucana PLC 0.2%
Value $3.696M Shares 5,599,999 Est. Cost $9.47 Unrealized
Bolt Biotherapeutics Inc 0.2%
Value $3.581M Shares 2,754,437 Est. Cost $32.91 Unrealized
GERN Geron Corp 0.2%
Value $3.532M Shares 1,459,589 Est. Cost $1.40 Unrealized +60.0%
Agenus Inc 0.2%
Value $3.041M Shares 1,267,000 Est. Cost $2.07 Unrealized
CTI Biopharma Corp 0.1%
Value $2.464M Shares 410,000 Est. Cost $5.40 Unrealized
PDSB PDS Biotechnology Corp 0.1%
Value $1.883M Shares 142,635 Est. Cost $8.36 Unrealized -15.6%
Nucana PLC 0.1%
Value $1.584M Shares 2,400,000 Est. Cost $4.99 Unrealized
ObsEva SA 0.0%
Value $689K Shares 4,749,623 Est. Cost $13.49 Unrealized
Synlogic Inc 0.0%
Value $437K Shares 574,972 Est. Cost $9.38 Unrealized
Fusion Pharmaceuticals Inc 0.0%
Value $369K Shares 117,099 Est. Cost $6.28 Unrealized