Location: Menlo Park, CA
CIK: 0001631134 · Show all filings
Period: Q3 2022 (← Previous) (Next →)
Filing Date: Nov 8, 2022
Total Value: $1.719B (100.0% shares, 0.0% debt)
| Ticker | Issuer | Shares | Value | % | Est. Cost | Unrealized | Class | CUSIP |
|---|---|---|---|---|---|---|---|---|
| — | Karuna Therapeutics Inc | 2,073,124 | $466M | 27.1% | $32.21 | — | COM | 48576A100 |
| — | Cincor Pharma Inc | 6,079,949 | $200M | 11.6% | $18.81 | — | COM | 17240Y109 |
| NTRA | Natera Inc | 3,102,960 | $136M | 7.9% | $9.81 | +385.3% | COM | 632307104 |
| VERA | Vera Therapeutics Inc | 3,181,442 | $67.8M | 3.9% | $16.04 | +16.7% | CL A | 92337R101 |
| — | Aerovate Therapeutics Inc | 3,758,686 | $62.32M | 3.6% | $22.83 | — | COM | 008064107 |
| ASND | Ascendis Pharma A/S | 499,824 | $51.61M | 3.0% | $69.98 | — | SPONSORED ADR | 04351P101 |
| MRK | Merck & Co Inc | 583,468 | $50.25M | 2.9% | $79.67 | +0.9% | COM | 58933Y105 |
| SNY | Sanofi SA | 1,264,546 | $48.08M | 2.8% | $40.70 | — | SPONSORED ADR | 80105N105 |
| QQQ | Invesco QQQ Trust Series 1 | 150,000 | $40.09M | 2.3% | — | — | Put | 46090E103 |
| AZN | AstraZeneca PLC | 701,878 | $38.49M | 2.2% | $60.02 | — | SPONSORED ADR | 046353108 |
| XLV | Health Care Select Sector SPDR | 300,000 | $36.33M | 2.1% | — | — | Put | 81369Y209 |
| IWM | iShares Russell 2000 ETF | 200,000 | $32.98M | 1.9% | — | — | Put | 464287655 |
| — | Y-mAbs Therapeutics Inc | 2,194,278 | $31.64M | 1.8% | $26.75 | — | COM | 984241109 |
| UTHR | United Therapeutics Corp | 147,564 | $30.9M | 1.8% | $155.83 | +43.5% | COM | 91307C102 |
| GILD | Gilead Sciences Inc | 482,400 | $29.76M | 1.7% | $55.78 | 0.0% | COM | 375558103 |
| MRK | Merck & Co Inc | 300,000 | $25.84M | 1.5% | $79.67 | +0.9% | Call | 58933Y105 |
| BMRN | Biomarin Pharmaceutical Inc | 294,750 | $24.99M | 1.5% | $81.66 | +9.0% | COM | 09061G101 |
| — | CTI Biopharma Corp | 3,612,376 | $21.02M | 1.2% | $5.23 | — | COM | 12648L601 |
| — | Reata Pharmaceuticals Inc | 818,376 | $20.57M | 1.2% | $31.91 | — | CL A | 75615P103 |
| ISRG | Intuitive Surgical Inc | 96,300 | $18.05M | 1.1% | $214.77 | 0.0% | COM | 46120E602 |
| IRTC | iRhythm Technologies Inc | 140,095 | $17.55M | 1.0% | $132.47 | +9.0% | COM | 450056106 |
| DXCM | Dexcom Inc | 205,948 | $16.59M | 1.0% | $92.37 | -8.3% | COM | 252131107 |
| SRPT | Sarepta Therapeutics Inc | 141,440 | $15.63M | 0.9% | $76.94 | +31.0% | COM | 803607100 |
| CYTK | Cytokinetics Inc | 320,722 | $15.54M | 0.9% | $36.75 | +31.0% | COM | 23282W605 |
| — | Iveric Bio Inc | 820,665 | $14.72M | 0.9% | $16.85 | — | COM | 46583P102 |
| LLY | Lilly Eli & Co | 45,500 | $14.71M | 0.9% | $308.08 | 0.0% | COM | 532457108 |
| ZNTL | Zentalis Pharmaceuticals Inc | 583,357 | $12.64M | 0.7% | $26.86 | +1.8% | COM | 98943L107 |
| SNDX | Syndax Pharmaceuticals Inc | 525,002 | $12.62M | 0.7% | $18.70 | +20.0% | COM | 87164F105 |
| EW | Edwards Lifesciences Corp | 147,200 | $12.16M | 0.7% | $96.22 | 0.0% | COM | 28176E108 |
| — | Akouos Inc | 1,515,074 | $10.24M | 0.6% | $22.50 | — | COM | 00973J101 |
| RCUS | Arcus Biosciences Inc | 381,345 | $9.976M | 0.6% | $26.45 | 0.0% | COM | 03969F109 |
| — | Inozyme Pharm Inc | 3,655,308 | $9.796M | 0.6% | $16.71 | — | COM | 45790W108 |
| IDYA | IDEAYA Biosciences Inc | 654,756 | $9.769M | 0.6% | $12.99 | 0.0% | COM | 45166A102 |
| TVTX | Travere Therapeutics Inc | 394,678 | $9.725M | 0.6% | $24.87 | +3.9% | COM | 89422G107 |
| — | Prometheus Biosciences Inc | 139,774 | $8.248M | 0.5% | $28.23 | — | COM | 74349U108 |
| — | Inhibrx Inc | 450,177 | $8.081M | 0.5% | $24.41 | — | COM | 45720L107 |
| — | Nextcure Inc | 2,671,856 | $7.348M | 0.4% | $10.01 | — | COM | 65343E108 |
| — | Adicet Bio Inc | 491,965 | $6.996M | 0.4% | $17.42 | — | COM | 007002108 |
| FULC | Fulcrum Therapeutics Inc | 797,262 | $6.45M | 0.4% | $7.16 | 0.0% | COM | 359616109 |
| — | Inhibrx Inc | 350,000 | $6.283M | 0.4% | $24.41 | — | Put | 45720L107 |
| — | Nucana Biomed | 5,599,999 | $5.852M | 0.3% | $9.47 | — | SPONSORED ADR | 67022C106 |
| — | Chinook Therapeutics Inc | 287,901 | $5.66M | 0.3% | $17.58 | — | COM | 16961L106 |
| RGNX | Regenxbio Inc | 213,959 | $5.655M | 0.3% | $32.39 | -8.4% | COM | 75901B107 |
| GRTX | Galera Therapeutics Inc | 3,083,712 | $5.366M | 0.3% | $12.19 | -88.4% | COM | 36338D108 |
| IMTX | Immatics NV | 532,516 | $5.325M | 0.3% | $11.23 | -3.9% | SHS | N44445109 |
| ARQT | Arcutis Biotherapeutics Inc | 274,330 | $5.242M | 0.3% | $22.66 | 0.0% | COM | 03969K108 |
| — | Agenus Inc | 2,437,465 | $4.997M | 0.3% | $2.01 | — | COM | 00847G705 |
| INSM | Insmed Inc | 220,665 | $4.753M | 0.3% | $24.12 | -0.6% | COM PAR $.01 | 457669307 |
| — | Bolt Biotherapeutics Inc | 2,754,437 | $4.077M | 0.2% | $32.91 | — | COM | 097702104 |
| GERN | Geron Corp | 1,189,208 | $2.783M | 0.2% | $1.21 | +85.1% | COM | 374163103 |
| GERN | Geron Corp | 1,072,100 | $2.509M | 0.1% | $1.21 | +85.1% | Call | 374163103 |
| — | Nucana Biomed | 2,400,000 | $2.508M | 0.1% | $4.99 | — | Ordinary Shares | GB00BYWYV |
| — | ImmunoGen Inc | 502,393 | $2.401M | 0.1% | $7.42 | — | COM | 45253H101 |
| — | NGM Biopharmaceuticals Inc | 150,000 | $1.962M | 0.1% | — | — | Call | 62921N105 |
| — | ObsEva SA | 4,749,623 | $675K | 0.0% | $13.49 | — | COM | H5861P103 |
| — | Synlogic Inc | 574,972 | $546K | 0.0% | $9.38 | — | COM | 87166L100 |
| PDSB | PDS Biotechnology Corporation | 142,635 | $424K | 0.0% | $8.36 | -49.2% | COM | 70465T107 |
| — | Fusion Pharmaceuticals Inc | 117,099 | $352K | 0.0% | $6.28 | — | COM | 36118A100 |