Samsara BioCapital, LLC Diversified Active

Location: Palo Alto, CA

CIK: 0001744967 · Show all filings

Period: Q4 2024 (← Previous) (Next →)

Filing Date: Feb 14, 2025

Total Value: $729M (100.0% shares, 0.0% debt)

Holdings (43)

SRRK SCHOLAR ROCK HLDG CORP 33.3%

Value $243M Shares 5,612,896 Est. Cost $9.37 Unrealized +247.5%

— CARGO THERAPEUTICS INC 8.7%

Value $63.67M Shares 4,415,689 Est. Cost $22.70 Unrealized —

SEPN SEPTERNA INC 8.7%

Value $63.4M Shares 2,768,520 Est. Cost $23.65 Unrealized 0.0%

MLYS MINERALYS THERAPEUTICS INC 8.6%

Value $62.47M Shares 5,074,916 Est. Cost $16.34 Unrealized -20.0%

NGNE NEUROGENE INC 5.4%

Value $39.25M Shares 1,717,127 Est. Cost $20.31 Unrealized +83.2%

UPB UPSTREAM BIO INC 5.0%

Value $36.45M Shares 2,217,146 Est. Cost $22.33 Unrealized 0.0%

LENZ LENZ THERAPEUTICS INC 3.9%

Value $28.49M Shares 986,981 Est. Cost $20.79 Unrealized +46.6%

ALMS ALUMIS INC 3.5%

Value $25.67M Shares 3,266,498 Est. Cost $12.13 Unrealized -17.4%

ACLX ARCELLX INC 2.7%

Value $19.45M Shares 253,641 Est. Cost $16.49 Unrealized +423.9%

ZYME ZYMEWORKS INC 2.0%

Value $14.64M Shares 1,000,000 Est. Cost $8.72 Unrealized +60.4%

JSPR JASPER THERAPEUTICS INC 1.7%

Value $12.5M Shares 584,642 Est. Cost $17.98 Unrealized +15.8%

— AVADEL PHARMACEUTICALS PLC 1.4%

Value $10.17M Shares 967,527 Est. Cost $14.06 Unrealized —

RYTM RHYTHM PHARMACEUTICALS INC 1.3%

Value $9.665M Shares 172,647 Est. Cost $17.86 Unrealized +209.3%

NKTX NKARTA INC 1.3%

Value $9.382M Shares 3,768,035 Est. Cost $21.30 Unrealized -85.5%

CTNM CONTINEUM THERAPEUTICS INC 1.2%

Value $8.626M Shares 588,816 Est. Cost $16.10 Unrealized -1.7%

PVLA PALVELLA THERAPEUTICS INC NE 1.1%

Value $8.154M Shares 679,486 Est. Cost $15.71 Unrealized 0.0%

— ACELYRIN INC 1.1%

Value $7.922M Shares 2,523,022 Est. Cost $19.61 Unrealized —

OKUR ONKURE THERAPEUTICS INC 1.0%

Value $7.088M Shares 824,155 Est. Cost $15.14 Unrealized 0.0%

CYPH LEAP THERAPEUTICS INC 1.0%

Value $7.022M Shares 2,442,352 Est. Cost $3.20 Unrealized -7.2%

ABVX ABIVAX SA 0.9%

Value $6.222M Shares 850,000 Est. Cost $10.70 Unrealized —

ACRS ACLARIS THERAPEUTICS INC 0.8%

Value $5.915M Shares 2,385,060 Est. Cost $2.16 Unrealized +15.2%

GOSS GOSSAMER BIO INC 0.8%

Value $5.545M Shares 6,130,268 Est. Cost $1.15 Unrealized -25.6%

CLYM CLIMB BIO INC 0.6%

Value $4.696M Shares 2,609,114 Est. Cost $6.66 Unrealized -45.6%

— VERONA PHARMA PLC 0.6%

Value $4.534M Shares 97,625 Est. Cost $6.18 Unrealized —

— INOZYME PHARMA INC 0.6%

Value $4.328M Shares 1,562,500 Est. Cost $4.20 Unrealized —

— SUTRO BIOPHARMA INC 0.6%

Value $4.042M Shares 2,196,814 Est. Cost $7.26 Unrealized —

ARTV ARTIVA BIOTHERAPEUTICS INC 0.4%

Value $2.94M Shares 291,666 Est. Cost $11.59 Unrealized +3.6%

VTVT VTV THERAPEUTICS INC 0.4%

Value $2.855M Shares 206,784 Est. Cost $12.98 Unrealized +13.9%

TNGX TANGO THERAPEUTICS INC 0.3%

Value $1.947M Shares 630,000 Est. Cost $11.99 Unrealized -61.3%

DAWN DAY ONE BIOPHARMACEUTICALS I 0.3%

Value $1.867M Shares 147,319 Est. Cost $20.76 Unrealized -33.0%

IMTX IMMATICS N.V 0.2%

Value $1.408M Shares 198,000 Est. Cost $10.34 Unrealized -16.9%

PRME PRIME MEDICINE INC 0.2%

Value $1.183M Shares 405,228 Est. Cost $16.71 Unrealized -79.0%

TERN TERNS PHARMACEUTICALS INC 0.2%

Value $1.121M Shares 202,348 Est. Cost $21.92 Unrealized -69.1%

— HILLEVAX INC 0.1%

Value $827K Shares 399,637 Est. Cost $11.56 Unrealized —

CRIS CURIS INC 0.1%

Value $607K Shares 198,216 Est. Cost $4.29 Unrealized 0.0%

JANX JANUX THERAPEUTICS INC 0.1%

Value $603K Shares 11,263 Est. Cost $22.27 Unrealized +137.5%

— BOLT BIOTHERAPEUTICS INC 0.1%

Value $561K Shares 1,049,153 Est. Cost $23.95 Unrealized —

— LYRA THERAPEUTICS INC 0.1%

Value $406K Shares 1,965,689 Est. Cost $5.09 Unrealized —

— ALLAKOS INC 0.0%

Value $208K Shares 172,089 Est. Cost $59.62 Unrealized —

— KRONOS BIO INC 0.0%

Value $74,224 Shares 78,131 Est. Cost $29.87 Unrealized —

— ALLOVIR INC 0.0%

Value $34,581 Shares 82,336 Est. Cost $27.50 Unrealized —

— NUVATION BIO INC 0.0%

Value $30,667 Shares 133,333 Est. Cost $0.28 Unrealized —

SRZNW SURROZEN INC 0.0%

Value $2,140 Shares 99,999 Est. Cost $0.19 Unrealized —

Ticker	Issuer	Shares	Value	%	Est. Cost	Unrealized	Class	CUSIP
SRRK	SCHOLAR ROCK HLDG CORP	5,612,896	$243M	33.3%	$9.37	+247.5%	COM	80706P103
—	CARGO THERAPEUTICS INC	4,415,689	$63.67M	8.7%	$22.70	—	COM	14179K101
SEPN	SEPTERNA INC	2,768,520	$63.4M	8.7%	$23.65	0.0%	COM	81734D104
MLYS	MINERALYS THERAPEUTICS INC	5,074,916	$62.47M	8.6%	$16.34	-20.0%	COM	603170101
NGNE	NEUROGENE INC	1,717,127	$39.25M	5.4%	$20.31	+83.2%	COM	64135M105
UPB	UPSTREAM BIO INC	2,217,146	$36.45M	5.0%	$22.33	0.0%	COM	91678A107
LENZ	LENZ THERAPEUTICS INC	986,981	$28.49M	3.9%	$20.79	+46.6%	COM	52635N103
ALMS	ALUMIS INC	3,266,498	$25.67M	3.5%	$12.13	-17.4%	COM	022307102
ACLX	ARCELLX INC	253,641	$19.45M	2.7%	$16.49	+423.9%	COMMON STOCK	03940C100
ZYME	ZYMEWORKS INC	1,000,000	$14.64M	2.0%	$8.72	+60.4%	COM	98985Y108
JSPR	JASPER THERAPEUTICS INC	584,642	$12.5M	1.7%	$17.98	+15.8%	COM NEW	471871202
—	AVADEL PHARMACEUTICALS PLC	967,527	$10.17M	1.4%	$14.06	—	COM SHS	G29687103
RYTM	RHYTHM PHARMACEUTICALS INC	172,647	$9.665M	1.3%	$17.86	+209.3%	COM	76243J105
NKTX	NKARTA INC	3,768,035	$9.382M	1.3%	$21.30	-85.5%	COM	65487U108
CTNM	CONTINEUM THERAPEUTICS INC	588,816	$8.626M	1.2%	$16.10	-1.7%	CL A	21217B100
PVLA	PALVELLA THERAPEUTICS INC NE	679,486	$8.154M	1.1%	$15.71	0.0%	COM	697947109
—	ACELYRIN INC	2,523,022	$7.922M	1.1%	$19.61	—	COM	00445A100
OKUR	ONKURE THERAPEUTICS INC	824,155	$7.088M	1.0%	$15.14	0.0%	COM CL A	68277Q105
CYPH	LEAP THERAPEUTICS INC	2,442,352	$7.022M	1.0%	$3.20	-7.2%	COM NEW	52187K200
ABVX	ABIVAX SA	850,000	$6.222M	0.9%	$10.70	—	SPONSORED ADS	00370M103
ACRS	ACLARIS THERAPEUTICS INC	2,385,060	$5.915M	0.8%	$2.16	+15.2%	COM	00461U105
GOSS	GOSSAMER BIO INC	6,130,268	$5.545M	0.8%	$1.15	-25.6%	COM	38341P102
CLYM	CLIMB BIO INC	2,609,114	$4.696M	0.6%	$6.66	-45.6%	COM	28658R106
—	VERONA PHARMA PLC	97,625	$4.534M	0.6%	$6.18	—	SPONSORED ADS	925050106
—	INOZYME PHARMA INC	1,562,500	$4.328M	0.6%	$4.20	—	COM	45790W108
—	SUTRO BIOPHARMA INC	2,196,814	$4.042M	0.6%	$7.26	—	COM	869367102
ARTV	ARTIVA BIOTHERAPEUTICS INC	291,666	$2.94M	0.4%	$11.59	+3.6%	COM	04317A107
VTVT	VTV THERAPEUTICS INC	206,784	$2.855M	0.4%	$12.98	+13.9%	CL A NEW	918385204
TNGX	TANGO THERAPEUTICS INC	630,000	$1.947M	0.3%	$11.99	-61.3%	COM	87583X109
DAWN	DAY ONE BIOPHARMACEUTICALS I	147,319	$1.867M	0.3%	$20.76	-33.0%	COM	23954D109
IMTX	IMMATICS N.V	198,000	$1.408M	0.2%	$10.34	-16.9%	SHS	N44445109
PRME	PRIME MEDICINE INC	405,228	$1.183M	0.2%	$16.71	-79.0%	COM	74168J101
TERN	TERNS PHARMACEUTICALS INC	202,348	$1.121M	0.2%	$21.92	-69.1%	COM	880881107
—	HILLEVAX INC	399,637	$827K	0.1%	$11.56	—	COM	43157M102
CRIS	CURIS INC	198,216	$607K	0.1%	$4.29	0.0%	COM	231269309
JANX	JANUX THERAPEUTICS INC	11,263	$603K	0.1%	$22.27	+137.5%	COM	47103J105
—	BOLT BIOTHERAPEUTICS INC	1,049,153	$561K	0.1%	$23.95	—	COM	097702104
—	LYRA THERAPEUTICS INC	1,965,689	$406K	0.1%	$5.09	—	COM	55234L105
—	ALLAKOS INC	172,089	$208K	0.0%	$59.62	—	COM	01671P100
—	KRONOS BIO INC	78,131	$74,224	0.0%	$29.87	—	COM	50107A104
—	ALLOVIR INC	82,336	$34,581	0.0%	$27.50	—	COM	019818103
—	NUVATION BIO INC	133,333	$30,667	0.0%	$0.28	—	*W EXP 02/10/202	67080N119
SRZNW	SURROZEN INC	99,999	$2,140	0.0%	$0.19	—	*W EXP 08/01/203	86889P117